Dissertation
Dissertation > Medicine, health > Pediatrics > Children within the science > Department of pediatric respiratory and chest diseases

The Preliminary Study on the 5’ Regulation Region Deletion of iNOS Gene of Children Asthma

Author JinXiuHong
Tutor LiXiaoWen;WangQunSi
School Zhengzhou University
Course Human Anatomy and Embryology
Keywords inducible nitric oxide synthase asthma gene restrict fragment length polymorphism (RFLP) short tandem repeats (STR)
CLC R725.6
Type Master's thesis
Year 2006
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Background and objectives:Asthma is a kind of Chronic inflammation that eosinophils and mast cells and T cells participate in. Asthma is characterized by structural remodeling of the airway wall and nonspecific bronchial hyperresponsiveness that is caused by Chronic inflammation. Although environmental influences are important in the development of asthma, there is a strong genetic predisposition. Many studies by affected sibling and families identified aggregation of asthma. People determine that asthma is a kind of complex polygene inherited disease through gene scan and candidate gene technique. Both environmental factor and genetic susceptibility have their effect on the development of asthma. The

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