Dissertation > Medicine, health > Otorhinolaryngology > Rhinology,nasal disease > Nasal disease > Cerebrospinal fluid rhinorrhea

Spontaneous Cerebrospinal Fluid Rhinorrhea Review and 2 Cases Report

Author GuXiang
Tutor YangZuoZuo
School Zhejiang University
Course Otorhinolaryngology
Keywords Rhinorrhea Spontaneity Bone defect Intracranial infection Master Surgical repair Thesis Zhejiang University Increased intracranial pressure Endoscopic
CLC R765.24
Type Master's thesis
Year 2008
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Unlike other cerebrospinal fluid(CSF)rhinorrhea,the symptoms for spontaneous CSF rhinorrhea are not obvious except for rhinorrhea,for this reason,the condition is very easily been ignored by patients.However it may threaten the life whenever the patients suffered from the infection of upper respiratory,because the infection may cause meningitis through the defeat in the skull base.Moreover,this disease is difficult to be treated effectively due to the difficulties in locating the defeats precisely.So,the ways to find the anatomical location of the leak is the key point for the successful treatment of spontaneous CSF rhinorrhea.Here we report 2 cases of spontaneous CSF rhinorrhea and review documents for 52 cases of spontaneous CSF rhinorrhea during the past 10 years.According to the literature,the defeat of skull base varied in the 52 cases.Among them,22 (39.3%)were found in cribriform plate,17(30.4%)were in sphenoidal sinus,13(23.2%)were in cells ethmoidal,2(3.6%)in frontal sinus and 2(3.6%)in clivus.Coincidently,the defeats of the 2 cases were in cribriform plate and sphenoidal sinus,both with meninges hernia.More attention should be paid to these two weaknesses of skull base when evaluating the patients and determining the location of the defeats.In addition,many authors suggested that increased intracranial pressure(ICP) is closing associated with etiological factors,pathophysiology mechanisms,clinical manifestation and prognosis of spontaneous CSF rhinorrhea.We should also take care of the patients present high ICP,the later plays role both in increasing the achievement ratio of the repair surgery and reducing postoperative recurring rate.

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