The Clinical Observation of Treating Recurrent Oral Ulcer by Kou Yan Qing
|School||Guangzhou University of Traditional Chinese Medicine|
|Course||TCM Internal Medicine|
|Keywords||Kou Yan Qing Recurrent oral ulcer Traditional Chinese Medicine therapy|
[Objective]The morbidity of Recurrent oral ulcer is high,the pathogeny of it is complex,the recurrence rate of it is also high,and there is no specific to treat it.ROU belongs to the category of "Aphthae" in Traditional Chinese Medicine.There are therapeutic characteristics and advantages of treating ROU by traditional Chinesemedicine method,especially has an advantage of anti-recurrence.The objective of this study is to observe the curative effect of treating ROU by Kou Yan Qing,which is created by Prof.Huang Minghe with his experience.Our purpose is to explore a Traditional Chinese Medicine method to treat ROU,which has small side-effect,well curative effect and low recurrence rate.[Methods]In the clinical study,we randomly divided 60 patients into two groups.The patients were treated in the Digestion special clinic from Oct.2006 to Dec.2007 and their diagnosis were definite.One group is.the treatment group and the other is the control group,there are 30 person in each group.The patients of the treatment group were treated by Kou Yan Qing taken orally, the composition of Kou Yan Qing is Shu Di,Sheng Di,Mai Dong,Tian Dong,Huang Qin,Yin Chen,Tu Fu Ling,Pi Pa Ye,Zhi Ke,Dan Pi and Gan Cao.Kou Yah Qing was made in Traditional Chinese Medicine preparation room of Shenzhen TCM Hospital.The patients must take this drug lukewarm orally twice a day,that is to take 150ml in the morning and 150ml at night when the stomach is empty. The patients of the control group should take Levamisole(50mg Tid),VitC (100mg Tid)and VitB2(10mg Tid)orally every day.During this treatment, patients of two groups should stop taking other related medicine and stop using all the external drug to treat ROU,stop eating pungent and irritant food and keep enough sleep.Two weeks after this treatment,we will evaluate the situation of symptoms ease and ulcer healing,observe the security and follow up the situation of recurrence.At last,we will summarise the results of this observation.We will use Chi-square test to process the enumeration data and use t test to process the measurement data. [Results]Through the clinical observation and the statistical analysis,the result is that the clinical cure rate of the treatment group and the control group is 60.00%and 20.00%(P＜0.01).The difference between the treatment group and the control group of the clinical cure rate is very remarkable,and the clinical cure rate of the treatment group is obviously higher than the control group.The total effective rate of the treatment group and the control group is 91.33%and 70.00%(P＜0.05).The difference between the treatment group and the control group of the total effective rate is remarkable,and the total effective rate of the treatment group is higher than the control group.The total effective rate and the clinical cure rate of the treatment group treated by Kou Yan Qing taken orally is obviously higher than the control group treated by western medicine taken orally.There is not visible toxicity and side effects of Kou Yan Qing.[Conclusion]The clinical curative effect of treating recurrent oral ulcer by Kou Yan Qing taken orally is apparently better than treating by Levamisole, VitC and VitB2 taken orally.Kou Yan Qing has well curative effect on treating ROU,it can greatly improve patients’ symptoms with no visible toxicity and side effects,and with low recurrence rate.To define the pertinency of treating ROUby Kou Yan Qing taken orally and to find if it cloud be propagable, we should enlarge the clinical case and study on large sample.After this, we may could poularize this method for clinical application,economize the iatrical resource and get well social benefit.