Hospitalized Patients with Motor Complication of Parkinson’s Disease: A Pilot Analysis on Related Factors
|Keywords||Parkinson's disease Motor complications Gender Age Course of disease First symptom Smoke Drinking Comorbidities|
Objective: To try to find the relevant factors of motor complications in Parkinson's disease , a preliminary discussion of the links between the various factors . : 2009 to 2010 , the Second Affiliated Hospital , Zhejiang University School of Medicine, Department of Neurology, hospital diagnosis of Parkinson's disease , 143 patients with Parkinson's disease motor complications and its forms are grouped according to whether they occur , record the gender , age , age of onset , duration of disease, the first symptom , smoking and drinking history and comorbidities , use of SPSS19 factors between groups ANOVA analysis of variance , t tests, nonparametric tests , chi-square test of fourfold table , Cox regression analysis , Logistic regression analysis , P lt; 0.05 indicates a statistically significant difference , the results list and mapping display . Results : The duration of disease in motor complications (P = 0.000) and dyskinesias (P = 0.001) difference in distribution between the groups was statistically significant between groups in motor complications (P = 0.000) (P = 0.001) and dyskinesias the central tendency of the difference was statistically significant ; long - term history of alcohol consumption and motor complications of Parkinson's disease was negatively correlated [ OR = 0.32 ( 0.10-0.99 ) , P = 0.039 ] ; urinary tract infection and Parkinson's disease movement complications [ OR = 1.08 (1.00-1.17), P = 0.031] and dyskinesias [ OR = 16.38 ( 2.03-131.85 ) , P = 0.025 ] were positively correlated . An independent risk factor for motor complications in Parkinson's disease patients , including women [ RR = 8.33 ( 2.22-33.3 ) , P = 0.002 ] , the first symptom the tremor [ RR = 4.35 ( 1.25-14.28 ) , P = 0.02 ] , duration of time long [RR = 1.24 / ( 1.10-1.41 ) , P = 0.001] , cardiac disease [RR = 14.29 (2.12-100), P = 0.007]; dyskinesias in Parkinson's disease patients were independent risk factors for the duration of time long [ RR = 1.51 / ( 1.05-2.17 ) , P = 0.026 ] . The test the difference was not statistically significant . Conclusion: The incidence of motor complications of Parkinson's disease and dyskinesias extended with Parkinson's disease course and increased ; emergence of motor complications ( especially dyskinesias ) more easily associated with urinary tract infection ; women, the first symptom of tremor , longer duration , combined heart disease in patients with Parkinson's disease are more susceptible to motor complications ; longer duration in patients with Parkinson's disease are more susceptible to dyskinesias .