Dissertation
Dissertation > Medicine, health > Neurology and psychiatry > Neurology > Brain diseases > Paralysis agitans syndrome

Hospitalized Patients with Motor Complication of Parkinson’s Disease: A Pilot Analysis on Related Factors

Author LeiXiaoGuang
Tutor ZhangBaoRong
School Zhejiang University
Course Neurology
Keywords Parkinson's disease Motor complications Gender Age Course of disease First symptom Smoke Drinking Comorbidities
CLC R742.5
Type Master's thesis
Year 2011
Downloads 25
Quotes 0
Download Dissertation

Objective: To try to find the relevant factors of motor complications in Parkinson's disease , a preliminary discussion of the links between the various factors . : 2009 to 2010 , the Second Affiliated Hospital , Zhejiang University School of Medicine, Department of Neurology, hospital diagnosis of Parkinson's disease , 143 patients with Parkinson's disease motor complications and its forms are grouped according to whether they occur , record the gender , age , age of onset , duration of disease, the first symptom , smoking and drinking history and comorbidities , use of SPSS19 factors between groups ANOVA analysis of variance , t tests, nonparametric tests , chi-square test of fourfold table , Cox regression analysis , Logistic regression analysis , P lt; 0.05 indicates a statistically significant difference , the results list and mapping display . Results : The duration of disease in motor complications (P = 0.000) and dyskinesias (P = 0.001) difference in distribution between the groups was statistically significant between groups in motor complications (P = 0.000) (P = 0.001) and dyskinesias the central tendency of the difference was statistically significant ; long - term history of alcohol consumption and motor complications of Parkinson's disease was negatively correlated [ OR = 0.32 ( 0.10-0.99 ) , P = 0.039 ] ; urinary tract infection and Parkinson's disease movement complications [ OR = 1.08 (1.00-1.17), P = 0.031] and dyskinesias [ OR = 16.38 ( 2.03-131.85 ) , P = 0.025 ] were positively correlated . An independent risk factor for motor complications in Parkinson's disease patients , including women [ RR = 8.33 ( 2.22-33.3 ) , P = 0.002 ] , the first symptom the tremor [ RR = 4.35 ( 1.25-14.28 ) , P = 0.02 ] , duration of time long [RR = 1.24 / ( 1.10-1.41 ) , P = 0.001] , cardiac disease [RR = 14.29 (2.12-100), P = 0.007]; dyskinesias in Parkinson's disease patients were independent risk factors for the duration of time long [ RR = 1.51 / ( 1.05-2.17 ) , P = 0.026 ] . The test the difference was not statistically significant . Conclusion: The incidence of motor complications of Parkinson's disease and dyskinesias extended with Parkinson's disease course and increased ; emergence of motor complications ( especially dyskinesias ) more easily associated with urinary tract infection ; women, the first symptom of tremor , longer duration , combined heart disease in patients with Parkinson's disease are more susceptible to motor complications ; longer duration in patients with Parkinson's disease are more susceptible to dyskinesias .

Related Dissertations
More Dissertations