Dissertation > Medicine, health > Chinese Medicine > Traditional Chinese Medicine Obstetrics and Gynecology > Gynecological diseases > By disease > Menopausal syndrome

Clinical Observation of Tiaoshen Ningshen Decoction on Treatment of the Permenopausal Syndrome (Deficiency of Both Kidney Yin and Yang Syndrome)

Author ZhangZuo
Tutor LinJie
School Hunan University of Traditional Chinese Medicine
Course Chinese Gynecology
Keywords Perimenopausal syndrome Deficiency of both Kidney yinand yang syndrome TiaoShen NingShen Decoction Clinical efficacy
CLC R271.116
Type Master's thesis
Year 2013
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Objective:To observe the clinical efficacy of TiaoShen NingShen Decoction on treatment of the Perimenopausal syndrome which also named as deficiency of both Kidney yin and yang syndrome.Methods:60patients with perimenopausal syndrome were assigned randomly to treatment group (n=30) and control group (n=30).TiaoShen NingShen Decoction was used in the treatment group while Jia Rong piece was used in the control group. The change of TCM symptom scores, the Kupperman index (KMI), the endometrial thickness and the levels of serum E2, FSH and LH were observed after8-week continuous treatment. Changes in the TCM symptom scores and the Kupperman index (KMI) need to be observed in the patients with effective treatment after4-week drug withdrawal.Result:①The changes of the TCM symptom scores and the KMI:After the treatment, there was a statistically significant decrease in the two group’s TCM symptom scores and the KMI(P<0.05) and there were remarkable differences between the two groups.(P<0.05)②The changes of the TCM symptom scores and the KMI after4-week drug withdrawal:the difference of the clinical efficacy between TiaoShen NingShen Decoction and Jia Rong piece was statistically significant (P<0.05).③The changes of the endometrial thickness:there were no changes in the two groups’endometrial thickness after treatment which were no statistical significant (P>0.05);there was no significant difference between the two groups (P>0.05).④The changes of endocrine hormone:After the TiaoShen NingShen Decoction treatment, there was a rise in the E2levels and a decrease in the levels of FSH and LH which is statistically significant(P<0.05) compared with those before treatment; while the E2levels on patients who treated with Jia Rong piece has no statistical significance (P>0.05).There was a statistically significant decrease in the levels of FSH and LH (P<0.05)compared with those before treatment but it showed no statistical significance between the two groups (P>0.05).Conclusion:TiaoShen NingShen Decoction is effective for Perimenopausal syndrome patients and free of toxic side effect which also improved with low recurrence rate.It provides a better treatment method for clinical cases.

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