Dissertation
Dissertation > Medicine, health > Chinese Medicine > TCM oncology

A Correlation Study on CT Signs and Syndrome Differentiation of Chinese Medicine in the Late Stage of Central Type Non-small Cell Lung Cancer

Author HuangXuKuan
Tutor LinXueJuan; LiCanDong
School Fujian University of Traditional Chinese Medicine
Course Diagnostics of Chinese Medicine
Keywords central type non-small cell lung cancer CT signs of TCM syndromedifferentiation correlation
CLC R273
Type Master's thesis
Year 2012
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Objective:To investigate the moderate-late central type non-small cell lung cancer with TCM syndrome type CT features of correlation between Chinese medicine treatment for lung cancer, syndrome differentiation and provide objective basis.Methods:from2009December to201112menstrual operation or biopsy of60cases of histologically confirmed central undifferentiated small cell lung cancer patients with the clinical data of lung cancer, according to syndrome differentiation of traditional Chinese medicine TCM Syndrome Typing of standard, standard for TCM syndrome differentiation:according to the grouping of turbid phlegm obstructing lung type, type of qi stagnation and blood stasis, Qi deficiency type, lung yin deficiency type, Yin two deficiency and lung and kidney deficiency type two, the group of patients were treated by using GE Lightspeed Qx/I Plus64row spiral CT plain scan, dynamic enhancement, access to CT features, in combination with the clinical symptoms of the patients, using a double blind method for the spiral CT manifestations and syndrome type analysis of the relationship.Results:(1)the60cases of patients with CT signs with obstructive pulmonary emphysema, obstructive atelectasis, mark Ye Zheng, malignant hydrothorax demonstrated, there were42cases,38cases,35cases,31cases.(2)The60cases of patients with the syndrome type of traditional Chinese medicine with Qi deficiency and phlegm obstructing lung type many, there were20cases,18cases, obstructive pneumonia in Qi deficiency in common; obstructive atelectasis in Qi deficiency in significantly more than other disease type (P<0.01); obstruction pneumonia in the turbid phlegm obstructing lung type of significantly more than other syndromes (P<0.01); malignant hydrothorax in Qi deficiency in common. (3)CT manifestations of tracheal invasion phenomenon in Qi deficiency, phlegm obstructing lung type, type of qi stagnation and blood stasis in the more common, than other syndromes (P<0.05); vascular invasion in Qi deficiency is more common, than other syndromes (P<0.05).(4)The TNM tumor staging, turbid phlegm obstructing lung type in III the following to see more, lung and kidney deficiency type in stage two (TNM1) to see more, accounted for75%(6/8). Ye Zheng, spiculation and cavity formation in the syndrome type had no significant difference (P>0.05).Conclusion:(1) the middle and late stage central type non-small cell lung cancer CT features mainly manifested as obstructive emphysema, obstructive atelectasis, mark Ye Zheng, malignant pleural effusion.(2)The middle and late stage central type non-small cell lung cancer with TCM to Qi deficiency and phlegm obstructing lung type more common, where the Qi deficiency of main CT signs of obstructive pneumonia, obstructive atelectasis, malignant pleural effusion, turbid phlegm obstructing lung type is mainly manifested as obstructive pneumonia.(3)The TNM staging of lung and kidney deficiency type, two with stage IV common, turbid phlegm obstructing lung type in III below to see more.(4)The late stage of central type non-small cell lung cancer by TCM type and CT signs have certain relevance, can be used as a clinical syndrome differentiation and treatment and prognosis of a basis.

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