Dissertation > Medicine, health > Oncology > Genitourinary tumors > Urinary tumors > Kidney,renal pelvis tumor

Analysis of the Effect of Laparoscopic Nephron-sparing Surgery for Renal Tumors

Author ZhaoChunGuang
Tutor QiLin
School Central South University
Course Department of Urology
Keywords renal cell carcinoma laparoscopic nephron-sparingsurgery laparoscopic radical nephrectomy survival rate renal function
CLC R737.11
Type PhD thesis
Year 2012
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ObjectiveWe studied the safety of laparoscopic nephron-sparing surgery (LNSS) through the changing of the renal function of the operated kidney after LNSS, and evaluated the effect of laparoscopic nephron-sparing surgery (LNSS) both through the recurrence rate and the survival rate versus laparoscopic radical nephrectomy (LRN).Material and MethodsWe studied the tendency of operated renal function by performing SPECT in62cases treated with LNSS. We compared recurrence rates and survival rates between62pT1a cases treated with LNSS and49pT1a cases treated with LRN from2006.01to2009.12.ResultsThe ratio of GFR (GFR of the operated kidney/GFR of contralateral kidney, GFR%) of patients of pTl a with WIT (warm ischemia time) less than30minutes changed by time and finally to a stable value about86%-94%1year after LNSS, The GFR%of patients of pT1a with WIT more than30minutes also changed by time and finally waved to a value about67-73%1year after LNSS. The GFR%of patients of pTlb with a WIT more than30minutes changed by time and finally waved between45%-65%1year after LNSS. Through the comparison between pTl patients treated with LNSS and LRN, we found no difference in the recurrence rates and the survival rates.ConclusionLNSS in our hospital is proved to be effective and safe in treating pTl stage renal carcinoma, and provides functional advantage with the maximal preservation of operated renal function without compromising cancer control. LNSS is promising for the patient with appropriate indication as a standard choice.

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