TCM herbs combined with hyaluronic acid treatment of knee osteoarthritis clinical observation
|School||Hubei University of Chinese Medicine|
|Course||Traditional Chinese Medicine|
|Keywords||TCM herbs Sodium hyaluronate Osteoarthritis Knee|
Objective orthopedic knee osteoarthritis is a common disease, mainly for knee pain, swelling, joint movement disorder, most common in the elderly population, especially in obese women is more common in males. Knee osteoarthritis lingering illness repeatedly, longer course, there is no effective cure exact. With the deepening of the aging population, the incidence rate increased, to patients with serious physical, psychological and economic burden. According to the clinical treatment of this topic herbal combination of sodium hyaluronate topical treatment of knee osteoarthritis, knee osteoarthritis patients were observed severity index score and comprehensive treatment. By observing the clinical efficacy of this therapy for the treatment of knee osteoarthritis clinical guidelines to provide a reliable basis for proposals and applications. Methods This study is based inclusion and exclusion criteria of cases, from June 2009 to November 2010, observed from the First Hospital of Wuhan orthopedic clinic or hospital treated 240 patients with knee osteoarthritis. Order by patient treatment, all patients were randomly divided into treatment group and control group 1 and control group 2, the treatment group received topical medicine combined with hyaluronic acid treatment, the control group received a pure sodium hyaluronate treatment and control 2 patients received topical treatment of traditional Chinese medicine alone, each of the 80 cases, treatment 5 weeks. According knee osteoarthritis severity index table, respectively, from the degree of pain, walking conditions and daily activities after treatment were integral changes, compared to the integrated effect observed after treatment, and conduct safety assessments. Establish a database using SPSS17.0 software, group comparisons using paired t-test, comparison between groups using ANOVA, compared with Ridit level data analysis, measurement information and data using mean ± standard deviation (x ± s) expressed. Results 1. Knee osteoarthritis severity index: before treatment of knee osteoarthritis severity index points mean 17.79 ± 2.87, after treatment was 5.06 ± 2.45; were a group before treatment of knee osteoarthritis severity index points mean of 17.56 ± 2.68, after treatment 6.86 ± 3.33; second control group before treatment of knee osteoarthritis severity index integral mean of 18.51 ± 3.28, after treatment was 9.63 ± 4.49. Points to improve the treatment group was better than the other two groups, the difference was statistically significant (P lt; 0.01), while the control group 1 Points improve the situation better than the control group 2, the difference was statistically significant (P lt; 0.05). (2) Comprehensive Comparative efficacy: treatment group were clinically cured 41 cases, effective in 24 cases, improved in 12 cases, ineffective in 10 cases, total effective rate of 88.5%; were a group of clinical cure 26 cases, effective in 20 cases, improved in 11 cases, ineffective in 27 cases, the total effective rate was 67.9%; second control group were clinically cured 13 cases, effective in 13 cases, improved in 25 cases, ineffective in 34 cases, total effective rate was 60.0%. Comprehensive treatment group were significantly better than the two control groups (P lt; 0.01); control group 1 and 2 than in the control group, the difference was statistically significant (P lt; 0.05). Conclusion TCM herbs and sodium hyaluronate combination therapy methods knee osteoarthritis obvious effect, the method of Integrative Medicine complementary advantages, not only can play a characteristic of Chinese medicine expertise, but also non-invasive, inexpensive, easy to use features, worthy of further promotion and application.