Dissertation > Medicine, health > Chinese Medicine > Of Pharmacy > In drugs > Drug identification

Study on the Quality Standard of Fuyankangfu Tablets

Author ZhanXiaoMing
Tutor PanHongLin
School Hubei University of Chinese Medicine
Course Of Pharmacy
Keywords Fuyankangfu tablets HPLC Quality Control
CLC R286.0
Type Master's thesis
Year 2011
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Quality standards of modern medicine modernization of Chinese medicine research is an important aspect of Chinese medicine is to ensure safe, effective and important way. Fuyankangfu piece Ministry of Health Drug Standards drug positive standard fourth book (1994 edition) collection contains varieties, Patrina, Coix, Toosendan, Bupleurum, Citrus, skullcap, red peony root herbs by Qiwei processed into tablets for the clinical treatment of chronic pelvic inflammatory medicine. Ministerial standards reproduces microscopic identification and orange peel, skullcap by TLC, no content determination, and commercial products and ministerial standards have improved, Chinese Pharmacopoeia (2005 edition) required inspection items have also been revised. Fuyankangfu sheet quality standard for that product quality standards to adapt to the needs of modern medicine, according to the provisions of heavy metals examination, arsenic salt examination, qualitative identification research and increase its determination of active ingredients to ensure that in the clinical application safe and effective. Fuyankangfu piece heat and dampness, circulation and pain relief for Patrinia, Coix, Toosendan, Bupleurum, Citrus, skullcap, TPG Qiwei Chinese medicine. Including peony, orange peel, skullcap contains Paeoniflorin, hesperidin, baicalin has significant anti-inflammatory antimicrobial effect, experiment, select hesperidin, baicalin and Paeoniflorin as the main active ingredient of the preparation simultaneous determination, This ensures that the quality of the preparation. In this thesis, by country, \the qualitative identification of studies using high performance liquid chromatography baicalin, hesperidin, Paeoniflorin determination carried out, the results showed that baicalin, hesperidin, Paeoniflorin as the reference with acetonitrile-0.05mol / L potassium dihydrogen phosphate solution as mobile phase, detection wavelength to 231nm, using a gradient elution method, other than the standard method to construct multi-component while the product determination method, and through different manufacturers, different batches of samples were determined and analysis, research methods to build its determination. The study constructed the determination of baicalin, hesperidin, Paeoniflorin measured simultaneously, simple and fast. The medicine is used for quality control, to ensure that the medicine is safe and effective adaptation of modern medicine has important significance.

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