A Research of Synthetic Optimization of C6-Fluoroketone
|School||Nanjing University of Technology and Engineering|
|Keywords||C6-Flouroketone process optimization isomerization epoxidation catalyst yield|
C6-Flouroketone is considered to be the most promising Halon substitute but high cost of synthesis. This article reviewed the synthetic route and process of C6-Flouroketone, then applied the synthetic route of C6-Flouroketone developed by Nanjing University of Science&Technology and did process optimization of synthesis of perfluoro-2-methyl-2-pentene (D2) from perfluoro-4-methyl-2-pentene (D1), epoxidation of perfluoro-2-methylpent-2-ene and isomerization of epoxy compounds. The products were characterized by19F-NMR and GC.In the research of synthesis of perfluoro-2-methyl-2-pentene, A was used as catalyst and18-crown-6as additive. Reaction conditions which effect on the synthesis of D2from D1were investigated, including the amount of catalyst, reaciton temperature and so on, and we got the initial optimal conditions(因涉及申报专利申报,部分省略。).............catalytic activity.In the synthesis of epoxy compound,因涉及申报专利申报,部分省略)............iquid yielded97%by GC.In the research of isomerization of epoxy compound, tertiary amine was better than metal fluoride with shorter time as catylants, and unlike triethylamine, catalyst A was still in good yield while the mass of perfluoro-2,3-oxy-2-methyl-pentane turned to100g. By orthogonal experiment, we got the optimal condition of50℃,60r/s of stirring,2.5equivalent of catalyst A. The yield was98.5%by distillation. The catylast also could be reused for7times with good catalytic activity.