Dissertation
Dissertation > Medicine, health > Chinese Medicine > TCM Internal Medicine > Modern medicine, internal diseases

The Correlation Study of Traditional Chinese Medicine Syndrome Differentiation of Coronary Heart Disease with Acute Coronary Syndrome and Catgstatin

Author XiaoLei
Tutor WuYiNan
School Shandong University of Traditional Chinese Medicine
Course Chinese medical science
Keywords Coronary heart disease acute coronary syndrome TCMsyndrome catestatin High sensitivity C-reactive protein(HS-CRP)
CLC R259
Type Master's thesis
Year 2013
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Objective:Through testing the levels of the catestatin (CST), HS-CRPof coronary heart disease with acute coronary syndrome(CHD with ACS),weexplore the correlation between the levels of catestatin、HS-CRP andTraditional Chinese Medicine(TCM) syndrome of CHD with ACS.Method:60CHD with ACS patients are defined in clinic.Collecting thepatients’general information, including symptom,sign,tongue,pulse andother clinical informations,then we divide all the patients into twoclinical types of TCM syndrome:30cases of the heart Blood stasis syndromegroup,30cases of debility blood stasis syndrome meridian syndrome group.Thelevel of plasma catestatin protein is detected by enzyme-linkedimmunosorbent assay (ELISA).The level of plasma HS-CRP is detected byfluorescence immunoassay. We analyze these data with the statistics softwareSPSS l7.0.Results:1.TCM syndrome differentiation of CHD with ACS group and thehealthy control group, gender, age, statistics showed no significantdifference, comparable;2.The levels of plasma Catestatin protein、HS-CRPof CHD group was higher than the normal control group; the lipid indexes:Thelevel of blood TG, TC, LDL-C is higher than that of the healthy control group,the level of blood HDL-C was lower than the healthy control group.3.CHD groupof plasma Catestatin protein,HS-CRP,the levels of blood TC,TG,LDL-C,weresignificantly higher than that in healthy control group, the level of blood HDL-C was lower than that of the healthy control group;4.TCM syndromedifferentiation of CHD with ACS group between groups, the level of Catestatinprotein, HS-CRP and blood lipid had no difference in the ststisticalsignificance.Conclusion:1.The level of catestatin and HS-CRP in CHD with ACS groupis significantly higher than that in the normal control group;2. The levelof catestatin and HS-CRP in TCM syndrome differentiation of CHD with ACSis significantly higher than that in the normal control group;3.The levelof catestatin and HS-CRP has obvious correlation in CHD with ACS;4.The levelof catestatin and HS-CRP has no significant difference between the two TCMsyndrome groups.

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