Study on the Endometrial Receptivity of Patients oflnadequate Luteal Function with Deficiency of Kidney through Intrauterine Physiotherapy
|School||Shandong University of Traditional Chinese Medicine|
|Keywords||Kidney endometrial receptivity endometrial artery blood flow PI、RI TGF-β1 desmosomal connections Intrauterine Physiotherapy|
Objective: The observed intrauterine physiotherapy of luteal function is not healthykidney patients with endometrial transforming growth factor-β1(TGF-β1) expression andendometrial desmosomal connections change impact, to explore the Warming Nuangongimprove embryo implantation endometrium Yungby mechanism of action.Methods: Clinical study of68cases of luteal function is not healthy infertilitypatients, according to the random number table divided into two groups with the the kidneytreatment group (treatment group) and kidney treatment group (control group) wereintrauterine physiotherapy before treatmentseven days after ovulation, the conventionaldraw little endometrial tissue, using immunohistochemical detection of endometrialendometrial expression of TGF-β1and electronic lens was observed in desmosomesconnect; statistics on patients with kidney symptom integral, HCG day intrauterinefilmthickness, endometrial blood flow pulsatility index and resistance index. For intrauterinephysiotherapy with kidney medicine treatment and simple kidney medicine treatment of acycle, the between-group and within-group assessed the same way to the same beforetreatment.Results:(1) The two groups of patients with kidney deficiency symptoms improvedthan before treatment, but the treatment group compared with the control group, asignificant effect, syndrome Credits difference was statistically significant (P <0.05);(2)patients endometrialthickness than before treatment has improved, but the treatment groupHCG injection day endometrial thickness was significantly higher than that in the controlgroup (P <0.05);(3) The two groups of patients with uterine artery blood flow pulsatility index and resistance index than those before treatmentHowever, the treatment group wassignificantly better than the control group, the two groups have a significant difference (P<0.05);(4) two groups of patients with endometrial expression of TGF-β1has beenenhanced than before treatment, but the treatment group was significantlyenhanced in thecontrol group, the two groups have a significant difference (P <0.05);(5) two groups ofendometrial desmosomes connect after treatment group was significantly less than thepre-treatment group, the two groups have a significant difference(P <0.05).Conclusion: Intrauterine Physiotherapy can improve endometrial receptivity, itsefficacy mechanism may reduce endometrial PI and RI, TGF-β1expression in endometrialand reduce endometrial desmosomes connect.