Dissertation
Dissertation > Medicine, health > Chinese Medicine > Traditional Chinese Medicine Obstetrics and Gynecology > Modern medicine, obstetrics and gynecology disease

The Clinical Research on the Treatment of Sequelae of Chronic Pelvic Inflammatory Disease (Syndrome of Damp-heat and Blood Stagnation) with Pushen Pelvic Inflammation Capsule

Author LiuChunFen
Tutor WeiShaoBin
School Chengdu University of Traditional Chinese Medicine
Course Chinese Gynecology
Keywords sequelae of chronic pelvic inflammatory disease damp-heat and bloodstagnation syndrome the Pushen pelvic inflammation capsule Clinical research
CLC R271.9
Type Master's thesis
Year 2013
Downloads 14
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Objective:To evaluate the efficacy and security of Pushen pelvic inflammation capsule in treating sequelae of chronic pelvic inflammatory disease (syndrome of damp-heat and blood stagnation), by comparing with placebo capsule treatment, aim to provide clinical evidence for its application.Methods:40patients with sequelae of chronic pelvic inflammatory disease, which diagnosed as syndrome of damp-heat and blood stagnation according to TCM theory, were randomly divided into test group or control group equally, with double-blind, positive control method. Test group were treated with PuShen pelvic inflammation capsule, while control group with placebo capsule for8weeks. The clinical symptoms and signs were observed and effectiveness and security related dates were assessed of the two groups both before and after treatment.Results:(1) single symptom curative effect:all the symptoms in test group including lower abdominal pain, lumbosacral pain, excessive and abnormal leucorrhea, were alleviated significantly after the test; additionally, the curative effect of the test group was significantly better than that of the controlled group(p<0.05). Except for tidal fever and dry stool, other accompanied symptoms were improved significantly in test group (p<0.05), and there was significant difference between the two groups.(2) Primary syndrome curative effect:The evident cure rate in test group was50%, total effective rate was90%, while for control group was respectively20%and70%.The difference was statistically significant (P<0.05) in the same group. There was significant difference between the two groups, and the curative effect in test group on improving primary syndrome was superior to that of control group by the analysis of SPSS17.0(P<0.05). (3) Symptoms curative effect:of TCM:the evident cure rate in test group was45%, total effective rate was85%; while for control group was respectively15%and60%。The difference was statistically significant (P<0.05) in the same group. There was significant difference between the two groups, and the curative effects in test group on improving Symptoms curative effect of TCM was superior to that of control group by the analysis of SPSS17.0(P<0.05).(4) local physical signs curative effect:for the test group, the evident cure rate was40%, total effective rate was85%, while for control group was respectively15%and60%。 The difference was statistically significant (P<0.05) in the same group. There was significant difference between the two groups, and the curative effect in test group on improving local physical signs was superior to that of control group by the analysis of SPSS17.0(P<0.05).(5) Comprehensive curative effect:for the test group, the evident cure rate was40%, total efficiency rate was85%; While for control group was respectively10%and55%。 The difference was statistically significant (P<0.05) in the same group. The curative effect in test group on improving local physical signs was superior to that of control group by the analysis of SPSS17.0(P<0.05)。There was significant difference between the two groups.(6) Safety analysis:during the test, there were two cases of adverse events, one case in test group turned up Urinary tract infection, which had no relation with drugs. One case in control group turned up mild cold, which had no relation with drugs. There were5%incidence of adverse events totally, and its clinical application was safety.Conclusion:PuShen pelvic inflammation capsule was effectively worked for the sequelae of chronic pelvic inflammatory disease. It greatly alleviated the symptoms such as:the lower abdomen pain, lumbosacral pain, yellow, abnormally large amount, or smelly leucorrhea, the healing rate and total effective rate were superior to placebo capsule. It is safe and convenient in clinical application and worthy the further research and promotion.

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