Dissertation
Dissertation > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging > Ultrasonic diagnosis

The Role of Echocardiography in Atrial Fibrillation after the Radiofrequency Ablation of Left Atrial Appendage Andleft Atrial Morphology and Functional Changes

Author WangJing
Tutor SuMaoLong
School Xiamen University
Course Medical Imaging and Nuclear Medicine
Keywords Atrial fibrillation Left atrial echocardiography
CLC R445.1
Type Master's thesis
Year 2014
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Objective:Echocardiographic evaluation of cardiac function is one of the important means.To evaluate the characteristics of left atrial and left atrial appendage functional and structural variations in the patients with paroxysmal atrial fibrillation after radiofrequency ablation using echocardiography,and explore the relationship between radiofrequency and left atrial and left atrial appendage remodeling.Methods:42cases with a duration of one to five years in patients with paroxysmal atrial fibrillation, divided into two group:A group,21cases with paroxysmal atrial fibrillation before radiofrequency ablation (40mm≤the left atrium dimension<50mm), mean age (55.59±13.43years); B group,21cases, atrial fibrillation after radiofrequency ablation followed up for3months (40mm≤the left atrium dimension<50mm),15cases of sinus rhythm,6cases of recurrence,mean age (53.39±10.12years);C group was normal control group,30cases, the average age (48.12±15.56years).Obtain Data of left atrium end-systole area/volume(LAs-Area/Volume),left atrium end-diastolic area/volume(LAd-Area/Volume), left atrium volume and left atrium volume index(LAVI), left atrial filling fraction (LA-FF) and left atrial shortening fraction (LA-CF) by TTE respectively. Performing TEE to get maximum left atrial appendage end-systolic area (LAAa), maximum emptying speed(LAA-A), peak filling velocity (LAA-E), ejection fraction(LAA-EF), early passive shortening score (EASF), active shortening fraction (AASF) of left atrial appendage. Results:(1) Compare Group A to Group B,all the parameters reflected the left atrial appendage function LAA-EF, LAA-E, LAA-A, as well as the parameters of the left atrial function LA-EF, LA-FF, LA-CF were significantly lower (p<0.01); while the left atrial structure parameters LAd-Volume and LAVI were obviously enlarged(p<0.01);(2) Compared with Group C, all the indexes of Group A,the left atrial function, including LA-EF, LA-FF, LA-CF have lowed significantly (p<0.01);the left atrial structure,including LAd-Volume, LAVI have increased significantly (p<0.01).(3) Group B compared with Group C, the indexes of LA-EF, LA-FF, LA-CF, LAd-Volume, LAVI did not show a clear change(p>0.05).Conclusion:By comparing the differences among the groups, paroxysmal atrial fibrillation can lead to significantly changes in the incidence of left atrial anatomy, the function of left atrial and left atrial appendage has significantly decreased. Compared with before and after surgery of atrial fibrillation patients left atrial and left atrial appendage structure and function by echocardiography, radiofrequency ablation is an effective way to improve the left atrial and left atrial appendage remodeling with paroxysmal atrial fibrillation in patients.

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