Dissertation
Dissertation > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Heart disease > Arrhythmia > Tachycardia

Clinical Characteristics of Paroxymal Supraventricular Tachycardia Patients with Atrial Fibrillation

Author WuJing
Tutor XieRuiQin
School Hebei Medical University
Course Internal Medicine
Keywords Paroxysmal supraventricular tachycardia Atrioventricularnodal reentrant tachycardia Atrioventricular nodal reentrant tachycardia Atrial fibrillation Clinical characteristics Risk factors
CLC R541.71
Type Master's thesis
Year 2014
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Objective: Atrial fibrillation (AF) raises the mortality of cardiovasculardiseases, and is one of the independent risk factors of stroke. Among theparoxysmal supraventricular tachycardia (PSVT) patients, the prevalence rateof AF is higher than general population. Some studies present that PSVTradiofrequency ablation may eliminate AF recurrence among some patients.Our study aimed in recognizing the clinical characteristics of PSVT patientswith AF and the risk factors of AF recurrence after PSVT ablation. This wouldprovide help to discuss AF mechanism, and clinical policy of treatment ofPSVT with AF.Methods: The data collection was performed among455patientshospitalized in Cardiovascular Department of2ndHospital of Hebei MedicalUniversity from June1st,2009to Jan1st,2013. This study population consistedof455patients who had PSVT with (n=39) and without AF (n=416).Information of the studied patients collected included hospital admission Id,name, gender, age, occupation, date of PSVT radiofrequency ablation, onsetage of PSVT, duration of PSVT, height, weight, smoking or not, drinking ornot, heart rate at the onset of PSVT, combined cardiovascular disease or not,combined AF or not, left atrial diameter, left ventricular ejection fraction, leftventricular posterior wall thickness, combined spontaneous AF or not duringtransesophageal atrial pacing and cardiac electrophysiology. Foratrioventricular nodal reentrant tachycardia (AVNRT) patients, we recordedsome extra data including pathway number, pathway type, combinedatrioventricular reentrant tachycardia or not; for atrioventricular reentranttachycardia patients, we recorded pathway number, pathway location,combined with manifest pre-excitation or not, combined with atrioventricularnodal reentrant tachycardia or not. Spontaneous AF lasting more than30 seconds during ablation or explicit AF record was defined as AF.Patients were divided into two groups, AF group and non-AF group. Alldata were expressed as mean±SD. Comparison of the data measured wereanalyzed by independent t test for numerical data. For categorical variablesthe chi-squared test was performed. The logistic regression was used toanalyze the relationships between presentation with AF as dependent variableand possible predictors as independent variables. A p value<0.05wasconsidered statistically significant. All statistical analyses ware performed byusing the IBM SPSS20.0for Windows.Results: AF patients were younger than non-AF group patients (y/o,30.74±14.11vs36.37±14.50,P<0.05), patients with AF had greater BMIthan those without AF (kg/m2,25.04±3.33vs23.79±2.92, P<0.05). Caseswith AF had more male patients and smoking patients. It also shows that AFpatients had higher heart rate when PSVT onset than non-AF patients(188.97±23.83vs177.44±23.24,P<0.05). AF group had more AVRT patients.Univariable logistic regression analysis showed the same results as above.Multivariable logistic regression analysis excluded smoking and age of PSVTfirst onset.Conclusion:Atrial fibrillation in patients with PSVT was8.57%, andthis prevalence rate was higher than general population. PSVT patients withAF were found had more male patients, more AVRT patients, higher BMI,higher heart rate when PSVT onset. After PSVT ablation the patients had lessprobability to get AF recurrence, and we didn’t get the risk factors of AFrecurrence.

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