Dissertation > Medicine, health > Clinical > Diagnostics > Diagnostic Imaging

Imaging Studies on the Contribution of Orbital Division to Diagnosis of Orbital Tumor and Tumor-like Diseases

Author TuWenGang
Tutor YuYongQiang
School Anhui Medical University,
Course Medical Imaging and Nuclear Medicine
Keywords Orbital tumors Orbital infection Orbital partition Orbital anatomy Diagnostic Imaging
CLC R445
Type Master's thesis
Year 2009
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BACKGROUND AND PURPOSE: orbital tumors and tumor-like lesions common eye disease is a common cause of blindness, so early and accurate diagnosis is very important. Fine anatomical structure of the eyes, a wide variety of diseases, difficult to biopsy. With the method of application of the various imaging studies, especially MRI and CT technology in clinical diagnosis, clinical diagnosis of orbital tumors accuracy greatly improve. MRI as a safe non-invasive imaging method, having good soft tissue resolution and spatial resolution can be displayed lesion morphology, size, location, secondary changes of the surrounding structure can also be displayed. Imaging lesion localization general muscle cone inside and outside, before and after the orbital septum and periosteum gap reference. At present, domestic and foreign literature yet orbital four-quadrant Space the coordinates divided Act reported. Inherent anatomical characteristics of the orbital structure, the vascular system are mainly located in the orbital lateral part of medial optic nerve. This study will be the optic nerve is the origin, the establishment of a four-quadrant coordinate system, to further explore the distribution of the characteristics of the different orbital tumors and tumor-like lesions, in order to judge the source and nature of the lesions. Materials and Methods: Retrospective analysis of 77 cases confirmed by clinical follow-up and surgical pathology intraorbital tumors and tumor-like lesions imaging (CT and MRI). Bilateral optic nerve is the origin, divided into four quadrants of the orbit. MAIN OUTCOME MEASURES: the composition ratio of the orbital tumors and tumor-like lesions, lesions in the orbital space distribution with the relationship between the qualitative diagnosis, lesion density and changes in the signal characteristics. Results: Inflammatory pseudotumor of 21 cases (27.3%), cavernous hemangioma in 13 cases (16.9%), dermoid cyst and epidermoid cyst in 11 cases (14.3%), metastatic carcinoma in 6 patients (7.8%), meningioma, glioma, 4 cases (10.4%), mixed tumor of the lacrimal gland, lymphoma and 3 cases (7.8%), lacrimal adenocarcinoma lymphangioma 2 cases (2.6%) the other lesions 8 cases (10.4%). To the optic nerve to the origin of coordinates, distribution of lesions in the orbital quadrant as follows: within the next 20 cases, within the previous 11 cases, outside on the 12 cases the outside next 28 cases from six cases of optic nerve. Lacrimal gland tumors occur in the upper outer quadrant of the optic nerve tumors occurred in the center of the optic nerve. Inflammatory pseudotumor occurs mainly in the orbital medial quadrant, significant differences in the distribution of orbital cavernous hemangioma (X2 = 5.308, P = 0.023), and lymphatic system disorders is relatively specific difference (X2 = 4.725, P = 0.043). Compared with the lymphatic system disorders, cavernous hemangioma relative specificity orbital outer quadrant, but the difference was not significant (X2 = 4.321, P = 0.063). Conclusion: orbital image credits area of ??great significance for orbital tumors and tumor-like lesions source and nature of the judgment. Cavernous hemangioma, the majority of orbital primary tumor is usually located in the intraorbital the outside quadrant; compared with the disease of the lymphatic system, the relative specificity of orbital outer quadrant; orbital inflammatory pseudotumor specific, non-specific inflammation occurred inside the orbital distribution of metastases no obvious regularity.

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