Dissertation > Medicine, health > Obstetrics and Gynaecology > Obstetrics > Fetus

3D-MRI Investigation on Fetal Surface Malformations Vs.2d-MRI and 3D-US

Author PangYing
Tutor XiaLiMing
School Huazhong University of Science and Technology
Course Medical Imaging and Nuclear Medicine
Keywords Fetus Three-dimensional imaging Magnetic resonance imaging After-treatment
CLC R714.5
Type Master's thesis
Year 2011
Downloads 16
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Objective: To discuss the 3D-MRI fetal surface normal structure and deformity clinical value. Methods: 68 December 2009 to April 2011, the line of ultrasound and MRI fetal prenatal ultrasound diagnosis or suspected fetal surface malformations 36. 48 hours knowledgeable MRI examination of the fetus in the ultrasound. Aged 18.2-38 years old, with an average of 26.4 years of age, gestational age of 20-36 weeks, an average of 28.3 weeks. Three-plane positioning of the abdomen of pregnant women on the basis of a single-shot fast spin-echo sequence (SSFSE) underwent conventional the fetal axial plane, sagittal and coronal scan. Using thick layer of heavily T2-weighted imaging magnetic resonance imaging scans of fetal water. And using the three-dimensional fast imaging with steady-state precession (3D-FIESTA) sequence line fetal 3D-MRI workstation raw data line multi-plane reorganization (MPR), the volume of reorganization (VR), transparent mode, the MR virtual endoscopy (MRVE) 3D post-processing analysis. Ultra 3D-U.S., 2D-MRI, 3D-MRI and autopsy and follow-up results compared. Results: fetal autopsy results and follow-up after birth found 42 cases of fetal surface malformations. Including cleft lip and palate, facial excrescence one cases, small jaw, the alar collapse two cases, microtia cases, facial hemangioma two cases, microcephaly five cases of conjoined twins, teratoma cases Horseshoe varus foot four cases, the short limbs deformity three cases, urachal diverticulum, abnormal limb posture, upper limb absence of the three cases, 3 cases (toe), palm and fingers missing two cases. 3D-MRI/2D -MRI/3D-US correct diagnosis, misdiagnosis of fetal the surface deformity 38/29/39 at 0/0/1 at 4/13/2 at. The sensitivity, specificity, and accuracy were 90.5% / 69.1% / 95.1%, 100% / 100% / 99.8%, 99.3% / 97.7% / 99.5%. 2D-MRI and 3D-MRI sensitivity, accuracy rate statistically significant, the sensitivity, specificity and accuracy of 3D-MRI and 3D-US was no statistically significant difference. The one-stop 3D-MRI scans from complex fetal structural changes in the curvature of the surface, and can be as clear as the photos show the relationship between the surface characteristics of the fetus, the three-dimensional characteristics and spatial location. VR images can visualize the the fetal facial structure, such as the cheeks, ears, nose, nostrils and nose, jaw, lips, umbilical cord and lower extremities, MPR Figure ROIs at any angle of rotation. Conclusion: Fetal 3D-MRI imaging display the fetal surface normal structures and lesions better than conventional 2D-MRI, and the vision and soft tissue resolution superior to ultrasound, can be used as the fetal surface malformations diagnosed one of the imaging methods. Ultrasound diagnosis is difficult cases, 3D-MRI is an effective diagnostic methods supplemented.

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