Dissertation
Dissertation > Medicine, health > Oncology > Gastrointestinal Cancer > Liver tumors

Diagnosis of Hepatic Tumors and the Relationship of the Mode of the Contrast-enhanced Ultrasound and the Generation of the Tumor Vessel

Author ZhangShiMing
Tutor HuangDaoZhong
School Huazhong University of Science and Technology
Course Medical Imaging and Nuclear Medicine
Keywords Liver Malignancy CEUS Angiogenesis Quantitative Analysis
CLC R735.7
Type Master's thesis
Year 2011
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Objective: To investigate the value of ultrasonography in the evaluation of liver cancer angiogenesis. Method: observation of 103 cases, 111 of the ultrasound contrast enhancement of the lesion liver malignancies mode, color Doppler ultrasound contrast display for malignant vascular; and contrast and digital subtraction angiography (Digital subtraction angiography DSA) evaluation of the malignant tumors associated with a larger arteriovenous fistula detection rate. Results: CEUS flow grade and color Doppler flow grade, a statistically significant relationship between tumor size, and tumor boundary, no statistical significance between the degree of tumor differentiation. Color Doppler flow grade with larger diameter tumor ultrasound contrast flow grade. The performance of the ultrasound contrast can prompt the presence of arteriovenous fistula. Conclusion: CEUS can effectively evaluate tumor angiogenesis, contrast-enhanced ultrasound can show a larger arteriovenous fistula, ultrasound contrast patterns may reflect the presence of arteriovenous fistula. Objective: To evaluate ultrasound contrast quantitative analysis of value in the diagnosis of benign and malignant tumors of the liver. : January 2008 - November Tongji Hospital, 112 patients received ultrasound contrast angiography image TIC curve analysis, recording its peak intensity change (A) TIC slope (β), A β and other indicators. Benign and malignant lesions above indicators of differences, and differences in the statistical analysis and ROC curve analysis indicators, derived quantitative values ??for determining the most appropriate of benign and malignant lesions. Results: A significant value judgment benign and malignant lesions of the liver β and A · β and peak intensity with the delay of the intensity difference in the discrimination of benign and malignant lesions difference was statistically significant, β, A · β and peak The difference of strength and the strength of the delay period were the difference between benign and malignant tumors to identify 1.49,28.91,3.92 db. Hepatic hemangioma with hepatocellular carcinoma surrounding the center late arterial phase enhanced intensity difference discrimination both statistically significant, the difference is taken to distinguish between the two when 5.72db discriminating. Conclusion: CEUS in quantitative indicators to distinguish benign from malignant lesions valuable difference β and A · β and peak intensity and strength of the delay period were taken 1.49,28.91,3.92 db differential diagnosis to distinguish benign from malignant lesions, liver discriminating hemangioma and hepatocellular carcinoma surrounding the center late arterial phase enhancement the intensity difference take 5.72db when the difference between both.

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