The Analysis of Related Factors in Type 2 Diabetes with Depression
|School||Dalian Medical University|
|Keywords||Depression Type 2 diabetes Related factors|
Objective: To analyze the related factors in type 2 diabetes patients with depression. It will provide basis for clinical treatment, control disease effectively, and improve the prognosis and the quality of life.Methods: 447 hospitalized patients of type 2 diabetes were selected as the research object. Questionnaire survey was adopted. The survey items include gender, age, diagnosis age, education, occupation, marital status, and duration of diabetes, family history, monthly income, treatment, medical forms, blood glucose monitoring situation, diet and exercise control, hypertension and diabetic complications. At the same time we measured height, weight, waist, hip circumference, waist-hip ratio, glycated hemoglobin (HbA1c), fasting plasma glucose (FPG) and 2-hr plasma glucose (2hPG). The patients filled personally depression self rating scale (SDS). The scale includes 20 entries, divides into four grade ratings, and the total score is 80 cent. Depression severity index is total score divided by 80, and depression is defined when the depression severity index≥0.50.Results:1.The prevalence of depression in type 2 diabetes patients was significantly higher than the general population(48.3%), and it was higher in female, high cultural degree, low income level and white-collar worker. The differences was statistically significant, P < 0.05.2.Compared with the non-depression group, the hypertension rates of the depression group was higher (62.5% vs 39.0 %), the age was older, the course of disease was longer, and the BMI, HbA1c, FPG, 2hPG was higher (P < 0.05). The blood glucose monitoring proportion, diet control proportion, motion control proportion of depression group were significantly lower than the non-depression group.3.The prevalence of depression was different under different treatments. The result was oral medicine and insulin group (57.0%) > insulin group (42.1%) > oral medicine group (29.7%).4.Depression group had a high incidence of diabetic peripheral neuropathy and macroangiopathy, compared with the non-depression group, and the difference was statistically significant (P < 0.05). As well, depression group had a high incidence of diabetic retinopathy and diabetic nephropathy, but the difference was no statistically significant (P > 0.05).5.Along with the increasing of HbA1c, the prevalence of depression in patients with type 2 diabetes was heightened subsequently.6.Logistic regression showed that BMI, HbA1c were the independent risk factors of depression.Conclusion:1.The prevalence of depression in type 2 diabetes patients was significantly higher than the general population, and it was higher in population of female, high cultural degree, low income level, white-collar worker, treated by oral medicine and insulin.2.BMI, HbA1c were the independent risk factors of depression. We can reduce the prevalence of depression in type 2 diabetes through controlling the body mass index and glycated hemoglobin, thereby reduce the incidence of diabetic complications and improve the quality of life.