Dissertation > Medicine, health > Surgery > Surgical operation > Anesthesiology

The Efficacy Comparing of Sufentanil and Fentanyl Assisted by Propofol for Aponia Colonoscopy

Author PingZuo
Tutor JiaYuJie
School Dalian Medical University
Course Pathology and Pathophysiology
Keywords colonoscopy intravenous anesthesia sufentanil fentanyl propofol
CLC R614
Type Master's thesis
Year 2011
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Objective: Compare and observe the efficacy of different minidose sufentanil and fentanyl assisted by propofol for aponia colonoscopy.Methods: 200 patients undergoing aponia colonoscopy were randomly divided into two groups of 100 patients each, Group S: sufentanil and propofol; Group F: fentanyl and propofol. Anesthesia was induced with sufentanil 0.1ug/kg and fentanyl 1ug/kg intravenously in each group, 3min followed by propofol 2mg/kg was given intravenously within 30 sec. colonoscope was inserted when lose consciousness. Additional propofol 0.5mg/kg~~1.0mg/kg was given by limbs movement and eyelash reflex. The anesthesia stopped by ileocecal valve reached HR, SBP, DBP, SPO2, duration of action, recovery time, operation time, propofol dosage and side-effect were continuously recorded.Results: colonoscopy was successfully performed. There was no complication occurred in both groups by follow up. The duration of action, general reaction of patients, propofol dosage in group S were lesser than those in group F(P<0.05). The operation time remain no difference between two groups. MAP was decreased apparently in both group compared with preinduction(P<0.05). Spo2 was no obvious changed during colonoscopy in both groups(P>0.05).Conclusion: sufentanil and fentanyl assisted by propofol provides effective analgesia, lower dosage, fast consciousness recovery and adverse reaction, minimal respiratory depression in colonoscopy.

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