Hierarchical Assembly Of Amphiphilic Copolymer and Application
|Keywords||Amphiphilic copolymer Self-assembled micelles Multi- level assembly Pickering emulsifier Imprinted Sensor Glucose|
In recent years, amphiphilic block, random copolymer self-assembly of theoretical research work has made remarkable achievements. However, the self-assembled micelles applied research mainly concentrated on precise control of micellar structure and properties, experimental procedures cumbersome experimental conditions harsh. How to further expand the application of polymeric micelles self-assembly, self-assembly industry has become the focus of attention of scientists. Recently, various inorganic and organic nano-micron particles assembled into a multi-level application development self-assembled micelles and the model provides a feasible idea. Multi-stage assembly process is not only able to combine the advantages of an existing assembly, and the spatial arrangement of multi-dimensional or melt and be able to give the resulting multi-stage assembly of new properties and applications. Micro and nano particles on the surface or interface is mainly based on the orderly arrangement of induced self-assembly or assembly. This topic has a different design and synthesis of structural properties of amphiphilic random and alternating copolymers, in which the resulting self-assembled micelles (an assembly) to build a primitive, they were investigated by the interfacial tension at the oil-water interface driver secondary assembly, and the electrostatic force induced by the dielectric substrate surface of the electrode film deposition, thus pioneering self-assembled amphiphilic copolymer micelles in an emulsion and sensing fields. Specific studies include the following two parts: 1. Alternating copolymer P (St-alt-Ma-Dopa) multi-stage assembly and emulsifying application by ordinary radical copolymerization alternating copolymer poly (styrene-alt-maleic anhydride ) P (St-alt-Man), and dopamine aminolysis get amphiphilic copolymer P (St-alt-Ma-Dopa). In selective solvents (DMF / water) in the P (St-alt-Man) and P (St-alt-Ma-Dopa) by solution self-assembly, stable spherical nano-colloidal particles. P (St-alt-Ma-Dopa) colloidal particles having a surface activity, driven by the tension of the interface, re-assembly arranged on the oil-water interface. Thus, the two assembly process, the colloidal particles can be used as a novel particle emulsifier for the preparation of stable Pickering emulsions, that is P (St-alt-Ma-Dopa) colloidal solution as the aqueous phase, toluene an oil phase, obtained after a stable homogeneous oil-in-water Pickering emulsion. An assembly of the prepared P (St-alt-Ma-Dopa) colloidal particles have a salt concentration and pH responsiveness. The particle size and zeta potential at different salt concentrations and pH values ??showed the opposite variation. Pyrene as a probe, using fluorescence spectroscopy to characterize the P (St-alt-Ma-Dopa) hydrophobic and hydrophilic colloidal particles showed that hydrophilic colloidal particles increases with the increase of pH, salt concentration with the solution increases slightly weakened. Colloidal particle concentration and pH also affects the response of the oil-water interface in the assembly arrangement again, and as a particle emulsifier emulsifying properties. 2 electric induction molecularly imprinted polymeric micelles (MIPMs) MIP sensor assembly and its application to acrylate monomer and styrene was synthesized photo-crosslinked amphiphilic random copolymer. After acidification with lactic acid to glucose as the template molecule, the ethylene glycol monobutyl ether / water, and the copolymer obtained from the assembly of the positively charged, imprinted with glucose micelles, its shape, the size by dynamic light scattering ( DLS) and transmission electron microscopy (TEM) characterization OK. Negative electric field induced in the assembled micelles mobility to the working electrode and eventually deposited film on the electrode surface. The whole process is electrically induced amphiphilic copolymers multi-level assembly. Assembled micelles combined size and Zeta potential variation with pH values, we concluded that the mechanism of electrodeposition micelles. The deposited film formed by crosslinking through the light, a stable molecular structure imprinted membrane (MIP Film), wherein the template molecule extracted, it modifies working electrode, a molecularly imprinted sensor (MIP sensors), the template molecule has a good selectivity and responsiveness. Test results show that the sensor glucose linear response range between 0.2 到 8 mmol / L, a detection limit of 0.05 mmol / L, detection limit of 10 mmol / L. Thanks to the photo-crosslinkable polymer, blotting membrane and internal molecular recognition point is locked, so the sensor shows an excellent stability. In summary, two aspects of this research confirmed the multi-stage assembly of amphiphilic copolymers advantages for the self-assembly technology provides a new way of thinking.