Dissertation
Dissertation > Medicine, health > Of Medical > Radiation Medicine > Each location and course of disease X - ray diagnosis and therapy > Department of Cardiovascular

256 -slice CT coronary angiography pre- ECG-gated low-dose clinical study techniques

Author HuangGuiLing
Tutor SunGeXin
School Jilin University
Course Clinical
Keywords Coronary angiography Tomography X -line computer Pre- ECG-gated ECG-gated rear Effective radiation dose
CLC R816.2
Type Master's thesis
Year 2011
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Objective: With the multi-slice spiral CT coronary angiography (MSCTCA) success rate and image quality improved, and its clinical applications are increasingly widespread, but its higher radiation doses caused people's attention. Reported in the literature lead ECG-gated coronary angiography take axial scanning technology required to meet the clinical diagnostic image quality while effectively reduce the radiation dose. But in the past about low-dose coronary CT imaging technology research based on 64 multi-slice spiral CT. With 8 cm wide detector Philips 256-slice CT has been put into clinical use, but the radiation dose on the research is not yet over. In this study, the Philips 256-slice CT in both groups were treated with ECG-gated scans front and rear ECG-gated scans individuals who underwent radiation dose and image quality assessment. Methods: 10 December 2010 to our hospital 256-slice CT coronary angiography scan 60 patients were randomly divided into two groups of 30 cases, respectively, for the two groups of patients pre-ECG-gated scans and rear ECG-gated scan and assess radiation dose and image quality. Records generated by a computer volumetric CT dose index (CTDIVOL), with a scan length obtained by multiplying CTDIVOL dose length product (DLP), then calculate the effective dose (ED). Expression of subjects with an effective dose of radiation doses suffered. The average effective dose for the two groups were statistically analyzed to determine whether the differences were statistically significant. Image quality assessment is divided into subjective evaluation and objective evaluation. Refers to the objective evaluation of coronary artery cross-sectional images were selected on the appropriate region of interest and regions of interest were measured average CT, namely the ascending aorta and right coronary artery, left main and left anterior descending artery, the average CT value, and The average CT values ??were statistically analyzed to determine whether the differences were statistically significant. Subjective evaluation to assess the degree of coronary artery of the display section. According to the American Heart Association (AHA) classifies the coronary artery is divided into 16 segments. By two experienced physicians blinded diagnostic imaging method to score two sets of images, recording each group scores were statistically analyzed to determine whether the two sets of image quality score difference was statistically significant. Ratings are divided by the two co agreed after discussion. Results: The study concluded that the front door and back door control group control group mean effective radiation dose was (3.7 ± 0.9) mSv and (18.0 ± 6.5) mSv. The difference between the two groups was statistically significant (t = -11.82, p = 0.00 lt; 0.05), front door controlled 79.0 percent lower than the control. Front and rear control group control group objective image quality evaluation results: two aortic ROIs mean CT values ??were (342.0 ± 47.5) HU and (322.6 ± 37.7) HU, the difference between the two groups was not statistically significant (t = 1.75, p = 0.08 gt; 0. 05); groups right coronary artery ROIs mean CT values ??were (323.2 ± 71.8) HU and (306.9 ± 72.4) HU, no statistical difference between the two groups significance (t = -0.87, p = 0.38 gt; 0.05); left main area of ??interest groups mean CT values ??were (353.6 ± 57.6) HU and (326.0 ± 72.2) HU, the difference between the two groups was not statistically significant (t = 1.63, p = 0.10 gt; 0. 05); groups left anterior descending artery ROIs mean CT values ??were (307.8 ± 76.8) HU and (280.8 ± 75.5) HU, no statistical difference between the two groups significance (t = 1.37, p = 0.17 gt; 0.05). Coronary images between the two groups by t-test mean CT value difference was not statistically significant (P gt; 0.05). Subjective image quality scores between the two groups by non-parametric tests (Mann-Whitney test) showed no significant difference (U = -1.2, P = 0.19 gt; 0.05); groups can meet the diagnostic image quality requirements. CONCLUSION: ECG-gated rear compare pre ECG-gated coronary angiography in maintaining quality while reducing the radiation dose.

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