The Research on Evolution of Name and Principle Rule Prescription Medicine of Manic-Depressive Psychosis
|School||Guangzhou University of Traditional Chinese Medicine|
|Course||Chinese medical science|
|Keywords||manic-depressive psychosis concept etiological factor mechanism formula herb|
ObjectiveTo discuss the concept of manic disease, clinical manifestations, pathogenesis, therapeutic herbs and other therapies, to enhance the TCM understanding of mania disease, to expand the current idea of TCM diagnosis and treatment of mania and improve clinical efficacy.MethodFrom the ages (including the Warring States Period to the Republic) of all kinds of Chinese medicine literature works and case for Collection, on which the name of disease related to "Dian and Kuang" disease evolution, pathogenesis, therapy and other prescription treatments, to establish a database system. Analysis the treatment of prescriptions for mania disease and inferences drawn from traditional Chinese medicine diagnosis and treatment of manic patients studied by using statistical methods. Then, our past 2 years outpatient medical records were retrospectively reviewed madness, in order to disscuss the characteristics and prescription laws of mania symptoms.Result1 ConceptFrom the pro-Qin to the Sui and Tang Dynasties, "Dian" refers to epilepsy, "Kuang " refers to the term of the present manic, "epilepsy"refers to children with epilepsy; the Tang Dynasty, "epilepsy"has the meaning of mental illness, but not until the Song Dynasty it began to name as truly "insane", alleged mental illness. During Song era, Dian in different writings means both mental illness and epilepsy, and "epilepsy " is used as the official name of disease at this time; " Kuang" of Song dynasty was of the term of the present "mania" after Jin and Yuan dynasties, the three basic concepts of Dian, Kuang, Xian can be distinguished. Both Dian and Kuang mean mental illness;Dian performance as "calm, but more than happy ", and the Kuang performance of "moving, but more anger"; in Ming and Qin dynasty more detailed description of Dian and Kuang, to realize that this disease was characterized by thinking, emotional, speech and acts disorders, Kuang is psychomotor excitement, characterized by impulsive behavior; Pathogenic wind "," pathogenic ghosts "and"evil haunting " can be incorporated into "Dian and Kuang"; dementia, dementia with epilepsy and "Hua Dian" should take ownership "Dian and Kuang"category.2 Etiological Factor and PathomechanismMania due to the long-lasting and intense emotional stimulation, leading to essence loss and upward adverse flow of qi; phlegm, pathogenic fire, blood stasis or pathogenic cold combining with each other, and finally disturbed mind. Or due to congenital insufficiency of origin essence and improper farti, which causes yin-essence loss, mental insufficiency, and then that pathogenic ghosts get a weak point to confuse mental. Essence loss is the basic of manic psychosis, while upward adverse flow of qi is its beginning. Upward adverse flow of qi and pathogenic fire usually exist side by side, for they interacts each other. Based on upward adverse flow of qi, body fluid forms phlegm, and blood forms stasis. Both could return to combine with fire, padding the deficiency and disturbing mind. The rule is Kuang resulting from yang exess, Dian resulting from yang deficiency. On the other hand, pathogenic cold makes body fluid form phlegm, which could disturb mind and result in manic.3 Prescriptions and other TreatmentsFrequency statistics obtained by successive high frequency treatment of mania disease drugs, which come to the dynasties of the drug characteristics and rules. Herbs of calming the mind, invigorating qi, removing heat, relieving exterior and resolving phlegm were higher frequencies. Essence loss and mental disturbed, yang excess and fire stagnated, pathogenic wind breaking through at a weak point or mental confusion due to phlegm is proved the main pathogenesis of mania from the ancient drug rules.In the ancient times, In addition to prescription treatment, acupuncture, moxibustion, conjuring and other methods were also used for clinical reference.4 Review Studies of Out-patient casesIn our out-patient treatment of manic patients, their high frequency of psychiatric symptoms were auditory hallucinations, irritability, torpid reaction, apathy and unexplainable smiling. It is clear that the majority of patients in our clinic were "Dian"; high frequency somatic symptoms were constipation, headache, feverish sensation in the palms and soles and sweating, The pulse condition was deep and thready, which suggesting that out-patients with deficiency of vital-qi; dim tongue and greasy tongue coating which suggesting that the common etiological factors were phlegm-damp and blood stasis. High frequency of drugs use fol lowed by were sedative drugs, warm the inner drugs, resolve phlegm-damp and reinforce body drugs etc.