Dissertation > Medicine, health > Ophthalmology > The general disease of the eye

Clinical Observation Analysis of Ocular Ischemic Syndrome

Author ZhangXiaoYan
Tutor MaXiang
School Dalian Medical University
Course Ophthalmology
Keywords Ocular ischemic syndrome / diagnosis Carotid stenosis Fluorescein angiography Clinical observation CT angiography
CLC R771
Type Master's thesis
Year 2011
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Objective: To investigate ocular ischemic syndrome in patients with clinical features and diagnostic methods. Methods: A retrospective analysis of 17 cases (19) of the OIS clinical data, all patients underwent history inquiry, the routine eye examination, carotid CT angiography (CTA) examination and carotid color Doppler system (CDFI ) examination. 18 eyes received fundus fluorescein angiography (FFA) examination. Check the results of count data as a percentage (%) that the measurement data were expressed as mean ± standard deviation, using SPSS 14.0 statistical software to analyze the degree of carotid stenosis relationship with ocular ischemic syndrome; contrast ipsilateral and contralateral carotid artery, internal carotid artery stenosis; comparing ipsilateral and contralateral carotid artery, internal carotid artery, ophthalmic artery peak systolic velocity (PSV). Diagnostic method based on the observed results are summarized. Results: 17 cases (19 eyes) ocular ischemic syndrome patients, male 10 cases (11 eyes) and 7 females (8 eyes), aged 51-75 years old, male to female ratio is almost equal to 16 (84.2 %) with varying degrees of vision loss as the main performance, there have been a transient amaurosis 14 (73.7%), eyes flashing 10 (52.6%), eye swelling and pain around the eyes with six (31.5%). The main signs are: 6 (31.5%) occurred iris neovascularization, including 5 eyes (26.3%) diagnosed as neovascular glaucoma, retinal changes 16 (84.2%) retinal vein dilation, 13 (68.4)% of the peripheral retinal spotting, 4 (21%) see the retinal artery pulsation, and cotton wool spots, arterial stenosis and other symptoms. Main FFA Performance: 18 (100%) showed an arterial \See No perfusion, and other performance capillary hemangioma, optic disc stained and so on. 19 (100%) carotid stenosis, CTA and analysis CDFI findings degree of carotid stenosis and ocular ischemic diseases high positive correlation between the rate (R = 0.792, P lt; 0.05). The group of patients ipsilateral carotid artery stenosis, carotid artery stenosis are more important than the contralateral stenosis, the difference was statistically significant (P lt; 0.05); this group of patients affected with contralateral carotid artery PSV contrast, the difference was not statistically significant (P gt; 0.05); while this group of patients with internal carotid artery contralateral carotid artery PSV contrast, the difference was statistically significant (P lt; 0.05); study group of patients suffering from side of the ophthalmic artery and contralateral ophthalmic artery PSV contrast, the difference was statistically significant (P lt; 0.05). All patients underwent treatment drugs vasodilator and microcirculation, 9 cases of carotid stenting, two routine carotid endarterectomy, iris neovascularization six eyes of four rows retinal photocoagulation, iris neovascularization subsided, secondary neovascular glaucoma five eyes underwent intraocular pressure lowering drugs, including two eyes with ciliary body cryotherapy, photocoagulation three eyes underwent carotid artery stenting, postoperative neovascular regression , normal IOP, visual acuity improved significantly. Poor prognosis, the current treatment can only alleviate the symptoms, visual acuity improved effective rate. Conclusion: The incidence of ocular ischemic syndrome is closely related to the degree of carotid stenosis, complex and diverse clinical manifestations, should be early diagnosis, early treatment; FFA examination revealed carotid stenosis is an important means of diagnosis of the disease.

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