Fractional excretion of uric acid and coronary heart disease clinical research

Objective: To investigate FEUA and coronary heart disease . Methods: 106 cases admitted between cases of coronary angiography , in accordance with the results of coronary angiography will be divided into non-CAD group and CHD group , CHD group divided into single-vessel disease in accordance with the number of diseased vessels , two lesions and vessel disease group , calculated in all cases Gensini score and the measured FEUA . Record other coronary heart disease risk factors , including gender, age, obesity , hypertension , type 2 diabetes , and dyslipidemia . Using t test , analysis of variance , single factor correlation analysis, multivariate stepwise regression analysis and logistic regression analysis to investigate the relationship between uric acid fractional excretion and coronary heart disease . The results : ( 1) the blood uric acid level of coronary heart disease group was significantly higher than that of non-CAD group ( P <0.05 ) , fractional excretion of uric acid was significantly lower than non-CAD group ( P <0.05 ) . Coronary heart disease among groups FEUA difference was statistically significant ( P <0.01 ) . ( 2 ) single factor analysis , fractional excretion of uric acid and coronary artery lesions and lesions Gensini score negatively correlated . ( 3 ) Multiple stepwise regression analysis (forward method) , triglycerides , body mass index , glycosylated hemoglobin significant risk factors for the severity of coronary lesions , fractional excretion of uric acid , and the severity of coronary lesions not related . (4) logistic regression analysis showed that , FEUA risk factors for coronary heart disease incidence . Conclusion: FEUA with the incidence of coronary heart disease -related , but not related to the degree of coronary lesions .