Dissertation
Dissertation > Medicine, health > Oncology > Genitourinary tumors > Female genital tumors > Uterine tumors

Clinical Analysis of Outcomes for Cervical Lymph Node Metastasis of Stage ⅠB-ⅡB Squamous Cancer of the Cervix after Surgery

Author AYiGuLi·MaiMaiTiAiLi
Tutor GuLiNa·KuErBan
School Xinjiang Medical University
Course Oncology
Keywords squamous cancer of the cervix cervical lymph node metastasis Risk factor Prognosis
CLC R737.33
Type Master's thesis
Year 2011
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Objective:This study was evaluate risk factors,distribution pattern, and Prognosis of patients cervical squamous cell cancer with cervical lymph nod metastasis at primary diagnosis after hysterectomy. Methods:Clinical data of stage IB-IIB cervical carcinoma patients with cervical lymph nod metastasis and cervical squamous cell cancer cases without distant lymph nod metastasis who had undergone radical hysterectomy and Bilateral pelvic lymph adenectomy for analysis at Xinjiang Tumor Hospital between 2003 and 2009 were analyzed. Results:The 3 year overall survival rate (OS) of cervical squamous cell cancer with cervical lymph nod involvement was 43.3%.Univariate analysis showed that risk factors of cervical lymph node metastasis of squamous cancer of the cervix were clinical stage, histological grade,serum level of squamous cell carcinom a antigen (SCC Ag)> 2μg/L before treatment, Tumor diameter, stromal invasion≥1/2, cancer embolus and positive iliac lymph node. Multivariate analys is revealed that the tumor size≥4cm, positive iliac lymph node and cancer embolus were significant risk factors of cervical carcinoma with distant lymph nod metastasis after hysterectomy. Serum level of squamous cell carcinom a antigen (SCC Ag)> 2μg/L before treatment, stromal invasion≥1/2 and cervical lymph nod metastasis were significant prognostic factors of cervical squamous cell carcinoma.Conclusion:Cervical lymph node and Supraclavicular lymph node metastases are both distant lymph node metastasis sites for patients with squamous cancer of the cervix. Tumor diameter≥4cm, cancer embolus and positive iliac lymph node were significant risk factors of cervical carcinoma with distant lymph nod metastasis after hysterectomy. Serum level of squamous cell carcinom a antigen (SCC Ag) > 2μg/L before treatment, stromal invasion≥1/2 and cervical lymph nod metastasis were significant prognostic factors of cervical squamous cell carcinoma.

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