Dissertation > Medicine, health > Surgery > Surgical operation > Anesthesiology > Local anesthesia > Anesthesia method

The Effects of the Ropivacaine for Postoperative Analgesia in Laparoscope Gynecologic Patients

Author LiuYanChao
Tutor JiangZuo
School Xinjiang Medical University
Course Anesthesiology
Keywords Ropivacaine Gynecology laparoscope surgery Postoperative analgesia
CLC R614.32
Type Master's thesis
Year 2011
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Objective To evaluate the analgesic effects of local infiltration or intraperitoneal injection of ropivacaine at the end of laparoscope surgery in gynecologic patients. Methods At the end of laparoscopic gynecologic surgery, in a double-blind, randomized manner,90 patients were divided into 3 groups:group A (n=30) Incision were treated with local infiltration of 0.5% ropivacaine (30 ml), group B (n=30) Both incision and intraperitoneal were treated with local infiltration of 0.5% ropivacaine (30 ml). group C(n =30) did not receive any injection as the control group. Pain score was assessed by using a visual analog scale (VAS)at 1,3,6,12,24 hours after surgery. Intravenous analgesic drugs was given if VAS>4. Postoperative nausea and vomiting(PONV) was rated. Sedative score was assessed by using a Ramsay Sedative scale.The additional analgesic drugs consumption after surgery and postoperative nausea, vomiting were also recorded.Blood cortisol concentration were measured in preoperative 0.5h and in postoperative 3h. Results The pain score of group A and group B were less than group C significantly at vary time after surgery (P<0.05).The number of patients in group A and group B consumed additional analgesic is significantly less than in group C. No influence had happened about ropivacaine on postoperative nausea, or vomiting(P>0.05). Blood cortisol concentration of group A and B in postoperative 3h were less in group C.Conclusion Introperitoned instillation of 0.5% ropivacaine after laparoscope surgery in gynecology is safe and effective to prevent postoperative pain, moreover, complications are rare. The combination of incision local infiltration and intraperitoneal infiltration was more effective for treatment of pain after laparoscopic gynecologic surgery than any sole method.

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