Dissertation
Dissertation > Medicine, health > Internal Medicine > Endocrine diseases and metabolic diseases > Metabolic diseases

Relationship between the Prevalence Study of Peripheral Artery Disease and Metabolic Syndrome among the Uygur Kazakh and Han Adults Lived in Xinjiang

Author PengZuo
Tutor MaYiTong
School Xinjiang Medical University
Course Internal Medicine
Keywords Peripheral artery disease Metabolic syndrome Data collection Uygur Kazakh
CLC R589
Type Master's thesis
Year 2011
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Objective: To investigate the prevalence and risk factors of peripheral artery disease (PAD), metabolic syndrome (MS) and peripheral artery disease complicated in metabolic syndrome among the adults lived in Xinjiang. Methods: Four-stage selected random samples maternal age 35 and over were used to analyze the prevalence and the relationship between the risk factors of peripheral artery disease and metabolic syndrome. The sampled adult population were collected 6 locality (Urumqi, Kelamayi, Fukang, the Turfan Basin locality, Hetian locality, Yili Kazakh autonomous prefecture) from 23 municipalities and 7 locality and 5 autonomous county in Xinjiang. The proportion of male to female accounted for 50% each. Each individual answered a questionnaire, received physical examination, biochemical indicator survey and ankle brachial index examination. To divide the patients who suffered PAD into two groups: one were complicated with metabolic syndrome and the other not. A logistic regression analysis was also made to identify possible risk factors and their powers on the prevalence of peripheral disease complicated in metabolic syndrome. Results:(1) A total of 14618 adults were surveyed. The prevalence of PAD was 5.3%,3.4% and 6.9% in male and female population. The prevalence of MS was 21.5%,24.5% for male and 19.0% for female in the total respectively. (2) The female PAD prevalence was higher than male in the same age, but the MS prevalence showed the male was much higher than female (P<0.05). (3) The prevalence of PAD was 7.1%,5.8% and 3.6% in Uygur, Kazakh and Han(P<0.05). (4) Divide the patients with PAD into two groups, one was suffer with MS and the other not. The statistic test on the age of the two groups showed that the age of the one complicated in MS, was elder than the other group (t=-6.57, P<0.001). (5) The common risk factors of PAD complicated in MS were systolic blood pressure, waist circumference, glucose, triglycerides; the other mutual risk factor of Uygur and Han were total cholesterol. While high-density lipoprotein was the common protect factor; the other unique risk factor of Han was uric acid; and the other protect factor of Han and Kazakh was gender (male). Conclusions:(1) The results of this study showed that the higher prevalence of PAD and MS in Xinjiang. (2) The prevalence of PAD and MS increased substantially with aging. (3) The highest prevalence of PAD was Uygur, the lowest was Han. (4) The three nations have common risk factors of PAD complicated in MS, there were also has its own. So the common control should be active on the basis, and note the difference among the control measures.

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