The Research of the Optimum Dose of Intrathecal Sufentanil in Low-dose Ropivacaine Spinal Anesthesia of Caesarean Section
|School||Central South University|
|Keywords||Ropivacaine Sufentanil Cesarean section Spinal anesthesia|
Objective: subarachnoid application of different doses of sufentanil in cesarean section a small dose of ropivacaine in spinal anesthesia , maternal, newborn reaction to explore a reasonable dose of sufentanil . Methods: 80 patients scheduled for elective cesarean section health expectant mothers , aged 20 to 39 years old, weight 54 ~ 90kg , ASA classification grade Ⅰ ~ Ⅱ , ??depending on the dose of sufentanil were randomly divided into four groups , each group in 20 cases. Group A was the control group (no sufentanil ) , the experimental group D groups were added of 2.5,5.0,7.5 ug sufentanil groups of local anesthetics are 0.75% ropivacaine cocaine 1.5ml 10% glucose injection to 2.5 ml . Anesthesia before and after the observation and recording HR , rr , SBP , DBP , ECG , SP02 , record sensory block plane , degree of motor block ( modified Bromage method ) , motor block , sensory block time and the beginning of the PCA time ; observe the nausea , vomiting , itching , chills and hypotension incidence and extent of neonates 1 minute and 5 - minute Apgar score . All data were expressed as mean ± standard deviation, application SPSS10.0 statistical software . Statistical analysis using t-test and variance analysis , p < 0.05 for difference , p <0.01 was considered significant . Results : The experimental group compared to the control group can achieve better anesthetic effect , which 5.0ug and 7.5ug able to meet the need for operation of small doses of ropivacaine spinal anesthesia , and can provide a good postoperative analgesia , significantly delayed the PCA time . 7.5ug 5.0ug than not significantly prolong the postoperative duration of analgesia and enhanced intraoperative anesthetic effect , there is a significantly higher incidence of pruritus and heightened degree of itching . Each group except itching other adverse reactions was no significant difference . Conclusion: In small doses of ropivacaine for spinal anesthesia , cesarean section , subarachnoid plus 5.0, 7.5 ug sufentanil able to obtain satisfactory anesthesia and postoperative analgesia . Which 5.0ug sufentanil dose is the most reasonable , which is likely to achieve a better balance between the anesthetic effect and adverse reactions .