Dissertation > Medicine, health > Surgery > Surgical operation > Anesthesiology

The Research of the Optimum Dose of Intrathecal Sufentanil in Low-dose Ropivacaine Spinal Anesthesia of Caesarean Section

Author LuoXiaoHui
Tutor LiaoQin
School Central South University
Course Clinical
Keywords Ropivacaine Sufentanil Cesarean section Spinal anesthesia
CLC R614
Type Master's thesis
Year 2009
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Objective: subarachnoid application of different doses of sufentanil in cesarean section a small dose of ropivacaine in spinal anesthesia , maternal, newborn reaction to explore a reasonable dose of sufentanil . Methods: 80 patients scheduled for elective cesarean section health expectant mothers , aged 20 to 39 years old, weight 54 ~ 90kg , ASA classification grade Ⅰ ~ Ⅱ , ??depending on the dose of sufentanil were randomly divided into four groups , each group in 20 cases. Group A was the control group (no sufentanil ) , the experimental group D groups were added of 2.5,5.0,7.5 ug sufentanil groups of local anesthetics are 0.75% ropivacaine cocaine 1.5ml 10% glucose injection to 2.5 ml . Anesthesia before and after the observation and recording HR , rr , SBP , DBP , ECG , SP02 , record sensory block plane , degree of motor block ( modified Bromage method ) , motor block , sensory block time and the beginning of the PCA time ; observe the nausea , vomiting , itching , chills and hypotension incidence and extent of neonates 1 minute and 5 - minute Apgar score . All data were expressed as mean ± standard deviation, application SPSS10.0 statistical software . Statistical analysis using t-test and variance analysis , p < 0.05 for difference , p <0.01 was considered significant . Results : The experimental group compared to the control group can achieve better anesthetic effect , which 5.0ug and 7.5ug able to meet the need for operation of small doses of ropivacaine spinal anesthesia , and can provide a good postoperative analgesia , significantly delayed the PCA time . 7.5ug 5.0ug than not significantly prolong the postoperative duration of analgesia and enhanced intraoperative anesthetic effect , there is a significantly higher incidence of pruritus and heightened degree of itching . Each group except itching other adverse reactions was no significant difference . Conclusion: In small doses of ropivacaine for spinal anesthesia , cesarean section , subarachnoid plus 5.0, 7.5 ug sufentanil able to obtain satisfactory anesthesia and postoperative analgesia . Which 5.0ug sufentanil dose is the most reasonable , which is likely to achieve a better balance between the anesthetic effect and adverse reactions .

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