Dissertation > Medicine, health > Chinese Medicine > TCM Internal Medicine > Modern medicine, internal diseases

Hypertension syndrome differentiation type correlation with risk factors and target organ damage

Author NingNing
Tutor ZhangYan
School Liaoning University of Traditional Chinese Medicine
Course Traditional Chinese Medicine
Keywords Hypertension TCM Syndrome Types Risk factors Target organ damage Correlation
CLC R259
Type Master's thesis
Year 2011
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Objective: To study the correlation of hypertension TCM syndromes and risk factors and target organ damage. Materials and Methods: This study 100 cases from March 2009 to May 2010 the Department of Cardiology of our hospital hospitalized patients have been diagnosed with hypertension. Developed hypertension TCM use EpiData3.1 software waiting retrospective questionnaire, clinical cases collected data entry questionnaire SPSSl7.0 statistical software for data analysis, research hypertension TCM syndrome and risk factors and target the correlation of organ damage. Results: 1. Traditional Chinese medicine syndrome and syndrome type: TCM type distribution the yin type (34) GT; anger hyperactivity type (25) GT; phlegm-dampness type (19 cases) gt; Yin and Yang deficiency syndrome (15 cases) gt; blood stasis (7 cases). The common symptoms of high blood pressure, dizziness, headache, fatigue, retching or nausea, backache, tinnitus, irritability, chest tightness, throat or dry mouth, mouth pain, soft knee syndrome distribution statistically significant difference (P lt; 0.01), anorexia statistically significant difference (P lt; 0.05). 2 risk factors of hypertension: the proportion of men and women in different syndromes was no significant difference (P gt; 0.05), the proportion of all ages were significantly different (P lt; 0.05) Obesity, smoking, drinking, obesity, family history of hypertension risk factors in various syndromes in the proportion of statistically significant difference (P lt; 0.05). Glucose metabolism in different TCM syndrome distribution ratio were significantly different (P lt; 0.05), total cholesterol (CHO) and low-density lipoprotein (LDL-C) levels between the various syndromes There were significant differences (P lt ; 0.05). (3) the level of blood pressure in patients with hypertension, classification and risk stratification: in different syndromes SBP levels P = 0.001 there was a significant difference, the DBP level P = 0.279 no significant difference. Different syndromes grade of hypertension comparison P = 0.018, P = 0.038 in risk stratification were statistically significant (P lt; 0.05) Hypertensive patients with target organ damage: the merger heart, brain, peripheral vascular damage in various syndromes have significant difference (P lt; 0.05), renal impairment; was no significant difference (P GT 0.05). The different syndromes end-diastolic left atrial (LA), end-diastolic left ventricular internal diameter (LVDd), interventricular septal thickness (LVSD) and left ventricular posterior wall thickness (LVPWd) were statistically significant (P lt; 0.05). In different syndromes between serum creatinine (Cr) were significantly different (P lt; 0.05) Conclusions: 1. Hypertension TCM syndromes distribution law. Yin the most widely distributed, followed by anger, hyperactivity, phlegm dampness, yin and yang, blood stasis. Common syndrome of hypertension in the four diagnostic waiting, symptoms of dizziness, headache, insomnia, fatigue is the most common, tongue and pulse distribution of red or dark yellow moss or less moss, pulse string breakdown the most common. Hypertension syndrome type classification of blood pressure levels and risk stratification significant difference. Grade Ⅰ, Ⅱ grade, layered risk, high-risk hypertension is more common in blood stasis, anger, hyperactivity type; the grade Ⅲ stratified into very high-risk hypertension more common in Yinxuyangkang type, phlegm dampness type. Significant correlation between the risk factors of hypertension and objective indicators between TCM. Before the age of 60 hypertensive patients located in anger hyperactivity and phlegm-dampness type more common after the age of 60 distributed in the yin, yin and yang deficiency and blood stasis is more common. Obesity, alcohol consumption in patients with phlegm dampness type distribution of the majority, the majority of patients who smoke in anger hyperactivity type, the majority of patients have a family history of high blood pressure in the blood stasis type. Associated with abnormal blood glucose in patients with hypertension in the hyperactivity type are mostly associated with dyslipidemia majority of phlegm dampness type. 5. Significant correlation between hypertension target organ damage and TCM syndrome type. Merger heart, brain damage to blood stasis more common; hyperactivity common with renal failure; combined with peripheral vascular damage phlegm dampness common.

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