Dissertation
Dissertation > Medicine, health > Chinese Medicine > TCM Internal Medicine > Modern medicine, internal diseases

Gui Shao Tong Luo Tang mixed cold and heat treatment of rheumatoid arthritis clinical research evidence

Author ZhuangXiuPing
Tutor LiuYing
School Shandong University of Traditional Chinese Medicine
Course Traditional Chinese Medicine
Keywords Rheumatoid Arthritis Mixed cold and heat proof Gui Shao Tong Luo Tang Methotrexate Hydroxychloroquine Clinical Evaluation
CLC R259
Type Master's thesis
Year 2011
Downloads 36
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Objective: To observe Gui Shao Tong Luo Tang treatment of rheumatoid arthritis (RA) is a mixed cold and heat proof of clinical efficacy, and to explore the mixed cold and heat proof RA pathogenesis and therapeutic principle . Methods: A randomized , controlled method, selected 60 cases of RA mixed cold and heat syndrome were divided into experimental group of 30 patients , I methotrexate and Gui Shao Tong Luo Tang treatment, the control group of 30 patients , I methotrexate and hydroxychloroquine therapy, 12 weeks , using the ACR20, DAS28, HAQ ( health Assessment Questionnaire ) , and Chinese medicine symptom efficacy standards , evaluation Gui Shao Tong Luo Tang evidence for RA mixed cold and heat treatment. Results : 1. ACR20 criteria were reached between the two groups and the total efficiency assessment , no significant difference (P gt; 0.05), DAS28 score, joint function , X-ray installment was no significant difference (P gt; 0.05). (2) The total effective TCM symptoms and HAQ score , the experimental group than the control group (P lt; 0.05); patients in both groups can improve joint pain, joint swelling, flexion and extension negative , morning stiffness , but in the local fever , bad cold , rainy days increase , heavy limbs , thirst , fever is not Young , skin color redness , sweating , etc., the experimental group than the control group (P lt; 0.05). 3 adverse reactions , the test group was 10% , 23% in the control group , the experimental group than the control group of high security , but there were no serious adverse reactions, the symptomatic treatment may disappear. Conclusion : The two groups of rheumatoid arthritis, mixed cold and heat proof , have a good therapeutic effect, but in TCM symptoms , the experimental group than the control group , showing , Gui Shao Tong Luo Tang mixed cold and heat treatment of RA certificate, efficacy, safety , in line with the etiology and pathogenesis of this disease .

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