Gui Shao Tong Luo Tang mixed cold and heat treatment of rheumatoid arthritis clinical research evidence
|School||Shandong University of Traditional Chinese Medicine|
|Course||Traditional Chinese Medicine|
|Keywords||Rheumatoid Arthritis Mixed cold and heat proof Gui Shao Tong Luo Tang Methotrexate Hydroxychloroquine Clinical Evaluation|
Objective: To observe Gui Shao Tong Luo Tang treatment of rheumatoid arthritis (RA) is a mixed cold and heat proof of clinical efficacy, and to explore the mixed cold and heat proof RA pathogenesis and therapeutic principle . Methods: A randomized , controlled method, selected 60 cases of RA mixed cold and heat syndrome were divided into experimental group of 30 patients , I methotrexate and Gui Shao Tong Luo Tang treatment, the control group of 30 patients , I methotrexate and hydroxychloroquine therapy, 12 weeks , using the ACR20, DAS28, HAQ ( health Assessment Questionnaire ) , and Chinese medicine symptom efficacy standards , evaluation Gui Shao Tong Luo Tang evidence for RA mixed cold and heat treatment. Results : 1. ACR20 criteria were reached between the two groups and the total efficiency assessment , no significant difference (P gt; 0.05), DAS28 score, joint function , X-ray installment was no significant difference (P gt; 0.05). (2) The total effective TCM symptoms and HAQ score , the experimental group than the control group (P lt; 0.05); patients in both groups can improve joint pain, joint swelling, flexion and extension negative , morning stiffness , but in the local fever , bad cold , rainy days increase , heavy limbs , thirst , fever is not Young , skin color redness , sweating , etc., the experimental group than the control group (P lt; 0.05). 3 adverse reactions , the test group was 10% , 23% in the control group , the experimental group than the control group of high security , but there were no serious adverse reactions, the symptomatic treatment may disappear. Conclusion : The two groups of rheumatoid arthritis, mixed cold and heat proof , have a good therapeutic effect, but in TCM symptoms , the experimental group than the control group , showing , Gui Shao Tong Luo Tang mixed cold and heat treatment of RA certificate, efficacy, safety , in line with the etiology and pathogenesis of this disease .