Dissertation > Medicine, health > Chinese Medicine > Chinese medicine clinic > Acupuncture, acupuncture therapy

Affection of Blood Grease, the Level of Serological Leptin and Fat Accumulate by Acupoint Catgut Treatment on Experimental Simple Obesity Rats

Author HuoXinHui
Tutor YinGaiZhen
School Xinjiang Medical University
Course Acupuncture and Massage
Keywords Embedding therapy Simple obesity Rats Leptin
CLC R245
Type Master's thesis
Year 2008
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Objective: To establish a simple obesity rat model to observe the effects of of catgut embedding of obese rats fat accumulation and leptin expression Preliminary catgut embedding lose weight mechanism . Methods : 50 SD rats to high fat diet combined with oral fed with homemade fat drink was modeling success 28 rats were randomly divided into a control group of obesity and catgut embedding therapy group . Catgut embedding treatment group to catgut embedding therapy, obesity control rats fed normal . After treatment, observation and body weight of rats , Lee's index , abdominal circumference , fat coefficient , total cholesterol ( TC ) , triglyceride (TG), low-density lipoprotein cholesterol ( LDL -C ) , serum leptin , the number of fat cells and diameter changes. Results: catgut embedding treatment of rats body weight , Lee's index , abdominal circumference , fat coefficient than the obese control group decreased significantly (P lt; 0.05); total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL -C), serum leptin levels and obesity control group was significantly decreased (P lt; 0.05); catgut embedding treatment group, the average diameter of the fat cells more obese control group was significantly decreased ( P lt ; 0.05 ) , the same vision , the fat cells elevated than obese control group (P lt; 0.05). Conclusion : The high fat diet combined with oral fed with homemade fat drink objects , can be quickly and effectively establish a rat model of obesity , a success rate of 56% . Embedding therapy can reduce the amount of obese rats have increased fat accumulation , regulation of blood lipid abnormalities increased , reducing leptin expression in obese rats . Its mechanism may be central stimulation of the hypothalamus , to regulate animal feeding behavior and fat metabolism , so as to achieve the purpose of weight loss .

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