The Analysis of Constitution of Cholelithiasis in Qingdao City and Jiaodong District from 1994 to 2004
|Keywords||Cholelithiasis Gallstone site Bile duct stones Ascariasis Cholesterol Bilirubin Small area analysis|
Objective: To investigate the formation and change of Shandong Province, Jiaodong region over the past decade (1994 to 2004) of gallstone disease. Methods: A retrospective survey collected in our hospital from 1994 to 2004 during hospitalization and confirmed by surgery clinical data of 2899 cases of gallstone disease patients, and randomly selected for the past five years (1999 - 12), stones specimens of 60 copies of the two groups of a total of 327 stones, sub roundworm foreign body stones group and roundworm stones group, bilirubin and cholesterol determination after computer finishing with SPSS12.0 software package for statistical analysis, and statistical results with comparative analysis of the 1991 data. Results: The overall gender composition of gallstone disease than the male to female ratio in 1991 1:1.38,2004 male to female ratio of 1:1.34, no statistically significant difference; gallstone disease between men and women in different parts of the 2004 group was significantly different, gallbladder stones, liver within the bile duct stones in gender statistically significant (P <0.05), while the gallbladder and biliary stones, simple common bile duct stones there is no statistically significant difference in gender. Simple gallstone peak age of onset is 50 to 59 years old; peak age of onset of the gallbladder and biliary stones, as well as simple common bile duct stones are more than 70 years old; the hepatolithiasis smaller peak age is 40-59 years old; stones parts compared the age distribution of the difference was significant (P <0.01); age distribution significantly compared with the 1991 set of statistics Move. The stone location gallbladder stones up to 1294/2899 (44.64%), followed by simple common bile duct stones in 658/2899 (22.70%). Gallstone (total) 1991 419/968 (43.29%) than in 2004, 1792/2899 (61.81%), gallbladder stones 247/968 (25.52%) was lower than in 1991, 2004, 1294/2899 (44.64%) ; common bile duct stones (total) 612/968 (63.22%) was higher than in 1991, 2004, 1156/2899 (39.88%), while pure common bile duct stones in 440/968 (45.45%) in 1991 than 2004, 658/2899 ( 22.70%); gallbladder and biliary stones 1991 172/968 (17.77%) and 2004 498/2899 (17.18%) no difference; hepatolithiasis 1991 109/968 (11.26%) and 2004 449/2899 (15.49%), no significant difference. Significantly increased the proportion of gallstone 1792/2899 (61.81%), and increases with age. Gallstones component analysis shows roundworm foreign body stones group gallstone ingredients all bilirubin; non roundworm stones group, 55.6% of the specimens to cholesterol as the main ingredient, 44.4% of the specimens to bilirubin as the main ingredient. Conclusion: the formation and change of the past decade (1994 to 2004) of gallstone disease in Shandong Province, Jiaodong region compared with the 1991 statistics, women gallbladder stones and intrahepatic bile duct stones proportions than men; elderly gallstone patients significantly increased; significantly higher proportion of gallstone composition; bile duct stones specimens of the past five years (1999 to 2005), the main component of the roundworm the foreign matter stones group bilirubin, rather than roundworms stones group composed of cholesterol or bilirubin, the analysis showed that: biliary ascariasis is still a major cause of the Shandong Province, Jiaodong area of ??primary extrahepatic bile duct stones, but the bilirubin level decreased compared to the 1950s.