Research on Nano-Hydroxyapatite/Chitosan Electro-compatible Composite Biomaterial

In this paper, the composition and structure of natural bone model , has excellent biocompatibility and biological activity of nano- hydroxyapatite (HA) and chitosan (CS) composite system as the research object , respectively, by in situ precipitation method situ Composite Method prepared nano- bio - electrical properties similar to natural bone hydroxyapatite / chitosan composite . By X -ray diffraction instrument (XRD) and transmission electron microscopy (TEM) study of the different preparation methods of nano-HA in the CS group body crystalline case and nano-HA particles in the CS group body dispersing properties of impact ; and study the different HA content of the mechanical properties of composite materials and bio- electrical properties ; bone material reference research hydroxyapatite / chitosan relevant laws between the micro- structure and properties of the composite . The test results show that situ composite method to improve the dispersibility of the particles in the nano-HA CS matrix effect , the lower the degree of crystallinity of HA , and the fine grains . The bending strength of the composites first increased and then decreased with increasing HA content , compressive strength of nonlinear elevated modulus changes situ composite method is more gentle situ precipitation method , the dielectric constant and piezoelectric constants have certain degree of reduction . When the HA and CS mass ratio is 0.1, the bending strength and modulus of the composite material of 75.9MPa and 3.3GPa and compressive strength and modulus of 47.5MPa and 2.2GPa , a dielectric constant at 1MHz to 12 , the piezoelectric constant d33 to 9.0pC / N, close to the level of natural bone . Due to the similarity with natural bone biomechanical and biological Electrocardiology , the composite material has potential uses in hard tissue repair .