Dissertation > Medicine, health > Chinese Medicine > TCM Internal Medicine > Modern medicine, internal diseases

Clinical Study on Relationship Between TCM Differentiation Syndromes of Type 2 Diabetes Mellitus and insulin resistance

Author WuXuePing
Tutor ZhouGuoYing
School Fujian College of Traditional Chinese Medicine
Course Traditional Chinese Medicine
Keywords Type 2 diabetes / diagnosis Syndrome type Insulin / blood Blood glucose / blood Lipids / blood Tumor necrosis factor / blood @ Insulin resistance
CLC R259.7
Type Master's thesis
Year 2001
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Background: Insulin resistance (IR), type 2 diabetes mellitus (DM 2 ) the basic features. IR, lipid metabolism, cytokines participate in DM 2 chronic vascular complications development. Objective: To investigate the DM 2 the TCM IR relationship, and explore the the the TCM type DM 2 chronic vascular complications relationship for the the DM 2 and the DM of 2 chronic vascular complications of the clinical syndrome reference indicators and prevention provide guidance for Integrative Medicine. Materials and Methods: WHO diagnostic criteria and TCM standards, selected the DM 83 cases 2 in patients for the study. 45 cases were male and 38 female; aged 40-70 years, with an average of 56.32 ± 12.17 years; course of 3 months -19 years, an average of 8.52 ± 6.43 years; 48 cases of chronic vascular complications, chronic vascular complications 35 cases. TCM Yin Deficiency and Heat 24 cases, 41 cases of Yin Deficiency type, yin and yang in 18 cases. The whole group is stasis syndrome type 54 cases, 29 cases of non-blood stasis syndrome. Normal control group of 30 patients, including 16 males and 14 females; aged 40-69 years old, with an average of 55.73 ± 11.68 years. Blood glucose was measured by glucose oxidase; Insulin was measured using chemiluminescence; lipids were measured by enzyme; tumor necrosis factor-alpha were measured using a double antibody sandwich enzyme-linked immunosorbent assay; using fasting glucose and fasting insulin multiplied by the reciprocal of the insulin sensitivity index; namely ISI = 1/FPG × FIns. Results: 1. DM 2 patients compared with the normal control group ISI reduced (P <0.01), the presence of lipid metabolism disorders [TG increased (P <0.of), I-IDL-C decreased (P <0.of Associated with chronic vascular complications than those without vascular complications the long duration scared knock. 05 plant various performance severity. 2. DM. TCM syndrome type I cited were lower than the control group (P knock .01), * in order for yin and yang> yin H Xure the Sheng type; syndrome type course with Yin thermal Sheng Group , Qi Group, the yin and yang group gradually extended; significant differences in O. 05, P knock. Than the normal control group of 01 eight card-type blood eve knock BU o, K increased (P <0.05, P <0.OI) and m Bu C to yin and yang group decreased significantly door knock. OI); 3. Blood stasis group than in the group of non-blood stasis long duration (P <0.01), and I * reduce (P <0.01); Where elevated (P <0.01), ** C decreased (P <0 .01), w * a serum concentration increased (P <0.), have significant differences; 4 blood stasis syndrome type in Chinese medicine are distributed Qiyinliangxu group yin and yang significantly higher than that of Yin Deficiency and Heat group threatened to knock. 05); the Qiyinliangxu group with the yin and yang group differences not significant door knocking. 05). 5. DM plant chronic vascular complications Qiyinliangxu group and the group was the highest of the yin and yang in Chinese medicine syndrome distribution frequency was significantly higher than that of Yin Deficiency and Heat group (P .01); Qiyinliangxu group with the yin and yang virtual group, the difference was not significant scare knock. 05) 6. DM; patients with blood stasis group than in the non-blood stasis group the incidence of chronic vascular complications increased significantly door knocking. 01); chronic vascular and Certification Section stasis syndrome incidence was significantly higher than the non-vascular and Certification Section door cut the throat. 01) 7. ISI with the course of the disease, n, w Bu * was negative off by (P <0.05, P <0. *), Was positively correlated with m Bu C (k0.05); called Bu a course of Wu was positively off by ( P <0.05, P <0) * BU C negatively correlated with u <0.05); knock C with a few positive correlation (P

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