Dissertation
Dissertation > Medicine, health > Oncology > Gastrointestinal Cancer > Liver tumors

Meta Analysis of Curative Effect of Traditional Chinese Medicine in Treating Late Patients with Primary Liver Cancer and Traditional Chinese Mediicine Thrombus Syndrome Analysis of Primary Liver Cancer with Portal Vein Tumor

Author YaoXiang
Tutor ChenLiangLiang
School Zhejiang University of Traditional Chinese Medicine
Course Integrative Medicine
Keywords Meta-analysis Later period Primary liver cancer Traditional Chinese Medicine Efficacy Primary liver cancer with portal vein tumor thrombus Syndrome Analysis
CLC R735.7
Type Master's thesis
Year 2010
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Objective: Meta-analysis software system evaluation of the efficacy of Chinese medicine treatment of advanced primary liver cancer; 2, retrospective analysis of primary liver cancer patients with portal vein tumor thrombus dialectical argumentation, of its TCM dialectical type and common summarize drug law; methods: 1, use the Meta-analysis of the efficacy of the software system evaluation in the medical treatment of advanced primary liver cancer, which Chinese medicine in the treatment of primary hepatocellular carcinoma with portal vein tumor efficacy evaluation published by 1999-2008 Chinese medicine treatment of advanced primary liver cancer and modern Western medicine treatment as the control group, randomized controlled study literature retrieval, according to the inclusion and exclusion criteria to determine the selected papers, quality assessment of selected literature, the literature outcome data admission, use RevMan4 .2 (Review Manager) software for statistical analysis, draw Meta-analysis results, and bias and sensitivity analysis. Collected with portal vein tumor thrombus cases of primary liver cancer Hospital of Zhejiang Province during 2003-2009, according to the selected exclusion criteria determine the selected cases, Chinese medicine dialectical type of retrospective of selected cases, Chinese medicine treatment ( were extracted using the weighted percentage method for statistical admission for the first time the traditional Chinese medicine prescription) and liver function Child classification derived primary hepatocellular carcinoma with portal vein tumor thrombus common TCM dialectical typing and common use of traditional Chinese medicine law. Results: 1 of the study were included 28 randomized controlled trials of Chinese medicine treatment of advanced primary liver cancer, the use of Meta-analysis to evaluate the efficacy of Chinese medicine treatment of advanced primary liver cancer: TCM Western medicine treatment group relative to the control group, tumor efficiency: the relative risk RR = 1.54,95% confidence interval (1.34-1.76), tumor stable rate: relative risk, RR = 1.58, 95% confidence interval (1.33-1.87), quality of life ( Karnofsky score) stable rate: relative risk RR = 1.49, 95% confidence interval (1.34-1.65) months' survival: relative risk RR = 1.66,95% confidence interval (1.32-2.09); respectively. hypothesis testing of the overall effect of the four indicators, P lt; 0.05, statistically significant; 2 Hospital of Zhejiang Province, with primary hepatocellular carcinoma with portal vein tumor thrombus were retrospectively analyzed 162 cases selected, the use of statistics, the weighted percentage method involves primary liver cancer with portal vein tumor thrombus common dialectical type: spleen deficiency, depression Syndrome, liver stagnation and spleen deficiency syndrome, spleen the wet storm certificate (Yun / group), and Qi stagnation, yin deficiency, damp-heat syndrome, blood stasis, qi stagnation certificates, etc.; commonly used in traditional Chinese medicine: Poria, Atractylodes, MI Ren, Polyporus, Gallus gallus, yams, August Sapporo, snake tongue grass, heterophylla, etc.; kind of Chinese medicine: Spleen Qi, Shugan Qi, detoxify, dampness drug, diuresis Shenshi, qi medicine, blood circulation; classification according to the Zhejiang Provincial Hospital of liver cancer TCM single disease standard, common syndromes type and its Chinese medicine: spleen deficiency syndrome: (including spleen deficiency, Spleen wet storm / the Yun / group, stagnation and spleen deficiency) Poria, Atractylodes, MI Ren, Polyporus, Gallus gallus, yams, August Sapporo, snake tongue grass, Prince Edward parameters such as gas Stagnation: (including gas Stagnation of liver qi stagnation) Bupleurum, turmeric, August Sapporo, white peony root, tangerine peel, Maozhaocao, Toosendan, Citrus aurantium, woody and other, blood stasis card: turmeric, red sage root, corydalis, red peony root, Citrus aurantium, Curcuma, peach kernel, safflower, Mitsubishi, Dan, Chuanxiong, fumarate, etc. Damp-heat: (hepatobiliary hot and humid, damp-heat syndrome): Bupleurum, peony root, capillaris, the sarmentosum money grass, Bodhisattva Scutellaria, Coptis, Phellodendron, River Park, herb, etc., Yin Deficiency: habitat, Rehmannia, red dates, white peony root, littoralis, Nansha ginseng, medlar, Ophiopogon , Dendrobium, Schisandra, turtle shell, Artemisia annua. Conclusion: Chinese medicine treatment of advanced hepatocellular carcinoma were evaluated: draw: 1.1 medicine treatment group tumor efficiency superior to Western medicine control group, in medicine or in combination therapy of advanced hepatocellular carcinoma in tumor efficiency better than Western medicine treatment of advanced liver cancer; Chinese medicine treatment group 1.2 the tumor stable rate is better than Western medicine control group, the treatment of advanced hepatocellular carcinoma tumor stable rate better than Western medicine treatment of advanced hepatocellular carcinoma in medicine or in Integrative Medicine; medicine treatment group 1.3 quality of life (Karnofsky stable) stable rate than Western medicine control group, Integrative Medicine in medicine or in the treatment of advanced liver cancer rate stability in the quality of life (Karnofsky stable) is superior to Western medicine treatment of advanced hepatocellular carcinoma. 1.4 Chinese medicine treatment group in the six months survival rate is better than Western medicine control group, Integrative Medicine in medicine or in the treatment of advanced liver cancer better than Western medicine treatment of advanced liver cancer survival rate in six months. Two pairs of primary hepatocellular carcinoma with portal vein tumor thrombus cases were analyzed retrospectively, to draw 2.1 common dialectical type: spleen deficiency, liver stagnation and spleen deficiency syndrome, spleen wet storm certificate most common, followed by liver Qi Stagnation, damp-heat syndrome Yin Deficiency; the 2.2 common Chinese medicine Category: Qi and spleen, liver qi, dampness drug, diuresis Shenshi etc.; the 2.3 Common Chinese medicine: Poria, Atractylodes, MI Ren, Polyporus, Gallus gallus, yam, August of Sapporo, snake tongue grass, Taizishen, Codonopsis;

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