Preliminary Study of the Hypomania Symptom Checklist-32 (Chinese Version) in Outpatients in the Department of Psychiatry and Psychological Medicine of General Hospital

The early [Objective] bipolar disorder often misdiagnosed as unipolar depression, which often results should be subject to patients after 8-10 years to get the right diagnosis and treatment. Prospective study found that the performance of hypomanic symptoms is likely to be diagnosed with bipolar disorder precursor symptoms. The hypomanic symptoms self-rating scale for early screening, may be early detection of potentially not get the proper treatment of patients with bipolar disorder. Hypomanic self-rating scale (HCL-32) as a self-rating scale, 32 assessment of hypomanic symptoms, 8 assessing severity and functional impact of translation to be used in multiple countries. The purpose of this study is that outpatient mood disorders in patients with sensitivity and specificity of the Chinese version of the HCL-32 applied to verify the reliability of the results of the evaluation, to provide a theoretical basis for scale applications in China. [Method] three cities (Shanghai, Hangzhou, Xi'an), the top three general hospitals consecutive outpatient psychiatric or psychological subjects. Inclusion criteria include: (1) signed informed consent; (2) the classification of mental disorders and the diagnostic criteria of the third edition (CCMD-3) mood disorder diagnostic criteria; (3) is not less than the age of 18 years old; (4) can be understood and compliance with the requirements of the research. Exclusion criteria included mental retardation, organic mental disorders, drug abuse, as well as low levels of education can not understand the patients with HCL-32 questionnaire. Enrolled patients completed the HCL-32 scale scores by psychiatric experts (five-year doctor of clinical experience and over) Check-in patients to make a definite diagnosis according to CCMD-3 diagnostic criteria, experts on patients with HCL-32 Rating no known situation. The data results were analyzed using the SPSS13.0. Eigenvalues ??greater than 1 factor correlation analysis, HCL-32 total score of items accumulate positive results. Subscale factor scores higher than 0.4 the composition of the positive result of the accumulation is subscale scores. HCL-32 total score and subscale scores of the reliability assessment selection Cronbach's alpha coefficient for homogeneity reliability indicators. [Results] 1010 patients enrolled in the study. 417 patients with bipolar disorder (236 patients with bipolar I type, 181 cases of biphasic type Ⅱ), 593 patients with depression. Use Kaiser varimax rotation matrix, results of eigenvalue gt; 1 factor of four, of which the first two factors highest eigenvalue. Factor 1 is identified as the \Factor 1 and factor 2 26.2% of the total variance. Factor loadings 0.4 entries subject factor 1 contains entries for 15, factor 2 contains entries for 7. The depressed patients HCL-32 total scores and subscale scores were significantly lower than bipolar disorder patients, bipolar Ⅰ and bipolar patients with type II statistical difference between no time. HCL-32 questionnaire internal consistency reliability coefficient of 0.84, factor 1 and factor 2 was 0.84 and 0.88, respectively, higher reliability of the questionnaire homogeneity. HCL-32 total score ≥ 14 is screening positive, the sensitivity of this standard HCL-32 was 69.30%, a specificity of 97.81%. Comparison of depression and bipolar patients HCL-32 to assess the percentage of the positive results of each project, 19 ratings statistical difference exists. [Conclusion] HCL-32 in the Chinese General Hospital outpatient test results show its reliability, validity, better screening of bipolar disorder can be used as auxiliary tools.