Theory and Clinical Research from the Toxic Gule Stasis Stagnation in Treating Children with Nephrotic Syndrome with Hypercoagulable State
|School||Chengdu University of Traditional Chinese Medicine|
|Course||Chinese Academy of Pediatrics|
|Keywords||Toxic gule stasis stagnation hypercoagulable state in children with nephrotic Yin ban zhu yu tang|
Objective:According to basic theory of TCM, described the occurrence of nephrotic syndrome with hypercoagulable state, according to syndrome differentiation, development of treatment programes, and through observation of clinical trials, objective evaluation of its efficacy, so as to better guiding clinical.Methods:Summary of ancient physicians in children with nephrotic syndrome with hypercoagulable state of awareness, make reference to modern literature, in combination with instructor’s clinical experience, proposed that in children with nephrotic syndrome with hypercoagulable state is caused by toxic glue stasis hysteresis. Based on etiology and pathogenesis created Yin ban zhu yu tang,It does this by clearing away heat detoxification and improving the blood circulation to treat the disease. It can make up for past deficiencies in knowledge. This study used the design, implementation and results of the analysis and interpretation of international standards and other aspects and the effectiveness of randomized controlled trials, Further evaluation Yin ban zhu yu tang’s treatment of children with nephrotic syndrome with hypercoagulable state of clinical efficacy, and explore their standardized treatment programs. For the treatment of children with nephrotic syndrome with hypercoagulable state to provide a more scientific treatment. Collection of 60 cases. Treatment with Western medicine for the comparison group, The treating group on the basis of the comparison group plus Yin ban zhu yu tang decoction.After 4 weeks,comparing the before treating and after treating of treating group. And carring out the comparison of symptoms efficacy and disease efficacy of treating group and comparison group after their treatments.Results:①. The comparison between the treating group and the comparison group and within the group are both having the statistics meanings (p<0.05) on the curing the proteinuria, hematuria and inspirits, dark or swarthy complexion, sore throat, wrong skin, numbness and other symptoms of traditional Chinese medicine and tongue coat, pulse.②. the disease effect: the total effective portion of the treating group is 93.33% while the total effective portion of the comparison group is 83.33%, the compartment between of the two groups has the statistic meaning (p<0.05).③.the symptom effect statistic:the total effective portion of the treating group is 96.67% while the total effective portion of the comparison group is 80%, the compartment between of the two groups has the statistic meaning (p<0.05.).④. the hypercoagulability effect:After treatment two groups’Fbg and D-D decreased significantly. Treating group’Fbg and D-D changed more significantly than the comparison group’(p<0.05).Conclusions:The generation of children with nephrotic syndrome with hypercoagulable state is close to toxic gule stasis stagnation. From the toxic gule stasis stagnation in Treating children with nephrotic syndrome with hypercoagulable state. Integrated Chinese and Western treatment of children with nephrotic syndrome with hypercoagulable state has a unique advantage, It is worthy of further study and clinical use.