Xianlinggubao Capsule on the Osteoarthrosis (Arthralgia) Efficacy
|School||Hebei Medical University|
|Course||Diagnostics of Chinese Medicine|
|Keywords||Xianlinggubao capsules Osteoarthritis The main symptoms Syndrome Treatment|
Objective: Osteoarthritis is a common disease of middle-aged disease. In recent years, many scholars of the disease were studied and discussed. The study was to investigate the treatment of osteoporosis proprietary Chinese medicines Xianlinggubao of capsules intervention in the treatment of osteoarthritis, and controlled clinical to explore Xianlinggubao capsule osteoarthritis syndrome clinical Puli Capsule effect, provide the basis for the drug to develop new uses, new methods and drugs for the prevention and treatment of osteoarthritis. Methods: National Eleventh Five topics osteoarthritis intervention control \Puli group of 80 people, urban and rural areas 40; blank control group of 40 people, urban and rural areas 20, each group of men and women 50%. Xianlinggubao group was given per person per oral Xianlinggubao capsules 1.5g, 3 times a day, and continued to take six months; fill in during the medication medication questionnaire, registration form of adverse drug reactions, drug payment recovery registration form and other related form, tracking medication. The Puli groups given per person oral Glucosamine Hydrochloride 0.24 g, day 3, continued to take three months; at the same time filled with the same group of Xianlinggubao form. Blank control group was not given any intervention drug or placebo, do not fill in any form. Years after the return visit, including the questionnaire and the second x-ray examination. According to the available information, compare the clinical efficacy of the two drugs. And the relationship between climate and efficacy analysis certificate, to explore the effect of the capsules Xianlinggubao treatment of osteoarthritis. Results: better 1 Xianlinggubao capsules of patients with osteoarthritis general the impact Xianlinggubao group and Puli group, patients overall mental condition, physical activity compared with baseline flexible and comfortable, strong voice, less smell and groaning sound. Study malaise, knees symptoms improved; joint paresthesia, limb numbness and other symptoms improve or disappear hold back inflation; alpine invasion, fatigue and other aggravating factors on the joints to reduce or disappear. Part of the syndrome such as insomnia, vertigo, tinnitus better. The control group patients have a poor mental state, malaise, body limp, and activity limitation compared with a year ago, is still in the doldrums, the side and sat up when you hear the sound of moaning, aggravating factors exist and no reduce the impact on the joints. Patients with osteoarthritis of the two medication groups generally significantly better than the control group. 2 Xianlinggubao capsule main signs and symptoms of osteoarthritis 2.1 to pain the impact Xianlinggubao group and the group of Puli pain in patients with varying degrees of improvement, Xianlinggubao group clinical control 50 cases, significant progress in 28 cases, 14 cases progress, 0 cases, the total efficiency of 100%. Puli were clinically in 39 cases, 20 cases of significant progress, progress in 12 cases, 3 cases, the total efficiency of 93.42%. Significant difference compared with the control group (P lt; 0.05); Xianlinggubao group Puli group there was significant difference (P lt; 0.05). 2.2 the swelling the Impact Xianlinggubao group and the Puli group swelling symptoms have improved, Xianlinggubao group of clinical control 47 cases, 31 cases of significant progress, progress in 18 cases and 1 case, the total efficiency of 98.97%. Puli were clinically in 13 cases, significant in 35 cases, progress in 21 cases, 7 cases, the total efficiency of 90.79%. Treatment is better than Xianlinggubao group swelling the Puli group, a significant difference (P lt; 0.05). 2.3 symptoms of morning stiffness morning stiffness the impact Xianlinggubao group and Puli group improved to varying degrees, XLGB group of clinical control of the 16 cases, 32 cases of significant progress, progress in 40 cases, 9 cases, the total efficiency 90.72%. Glucosamine group clinical control in 8 cases, 17 cases of significant progress, progress in 22 cases, ineffective in 29 cases, total effective rate of 61.84%. Significant difference (P lt; 0.05); medication group, Xianlinggubao group was significantly better than the therapeutic effect of morning stiffness Puli group compared with the control group, a significant difference (P lt; 0.05). 2.4 pairs of joint friction sound (sense) the impact of Faerie bone Celebrex group and the Portuguese established group joint friction sound (sense) significantly alleviate, Faerie bone Celebrex group clinical control 18 cases, significant progress in 27 cases, progress in 39 cases, ineffective in 13 cases, The total efficiency of 86.60%. Puli group clinical control 15 cases, significant improvement in 38 cases, to progress 19 cases, 4 cases, the total effective rate of 94.74%. Compare significant difference (P lt; 0.05); two medication groups, Puli group joint friction sound (sense) the treatment effect was significantly better than the Faerie bone Celebrex group, a significant difference (P lt; 0.05) with the control group . 3 Xianlinggubao capsules different syndromes in patients with osteoarthritis efficacy of liver and kidney deficiency tendons stasis clinical the Xianlinggubao group control 13 cases, effective in 23 cases, 2 cases, invalid 0 cases, spleen and kidney and losses virtual wet Note joints type of clinical control in 7 cases, 1 cases markedly effective in 4 cases, 3 cases of liver and kidney deficiency phlegm and blood hindered clinical control 8 cases, 19 cases, 2 cases, 4 cases. Glucosamine group liver and kidney deficiency the tendons and stasis clinical control five cases, 18 cases markedly effective in 3 cases, 3 cases, the spleen and kidney deficiency wet Note joints type of clinical control cases, 9 cases, 10 cases, ineffective 5 cases, liver and kidney deficiency Phlegm cross-resistance clinical control in 4 cases, 9 cases markedly effective in 3 cases, 6 cases. Liver and kidney deficiency the tendons and stasis type, type, and liver and kidney deficiency of spleen and kidney deficiency wet Note joints three syndromes of phlegm and blood resistance group, Xianlinggubao group were significantly better than the Puli group, a significant difference (P lt; 0.05). Xianlinggubao capsule on liver and kidney deficiency, tendons and stasis efficacy in patients with the most obvious, better than the spleen and kidney deficiency, wet Note joints type and liver and kidney deficiency, phlegm and blood hindered significant difference (P lt ; 0.05). Conclusion: 1 Xianlinggubao capsules clinical efficacy of osteoarthritis Indeed, no adverse reaction, can further promote the use of. 2 Xianlinggubao capsules of patients with osteoarthritis joint pain, swelling, morning stiffness, joint friction sound (sense) and other clinical symptoms improved significantly, which can effectively improve the quality of life of patients, to alleviate the suffering of patients. 3 Xianlinggubao capsules have different levels of efficacy of different syndromes in patients with osteoarthritis, especially for liver and kidney deficiency the tendons stasis efficacy in patients with more significant.