Dissertation > Medicine, health > Chinese Medicine > TCM oncology

Theoretical and Clinical Research on Spleen-tonifying, Dampness-resolving, Stasis and Toxin-removing in the Treatment of Advanced Colorectal Carcinoma

Author YuanDong
Tutor WangXingHua
School Nanjing University of Traditional Chinese Medicine
Course Clinical basis for TCM
Keywords Colorectal Cancer Later period Jianpihuashitang Stasis Decoction Chinese medicine Theoretical study Clinical observation
CLC R273
Type Master's thesis
Year 2010
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Objective: To observe Jianpihuashitang Stasis Decoction on the treatment of advanced colorectal cancer , and to explore its mechanism . Methods: 30 patients with advanced colorectal cancer were randomly divided into treatment group 15 cases , taking Jianpihuashitang stasis detoxification side , and the joint FOLFOX chemotherapy ; control group 15 cases , simple to FOLFOX chemotherapy . Two groups were compared remission of clinical symptoms before and after treatment to improve the general condition , changes in serum tumor markers and the extent of adverse reactions to chemotherapy , to quantify the score as efficacy evaluation and statistical analysis the two groups in terms of the differences in these indicators . Results : The treatment group of TCM syndromes effective rate of 86.67% in the control group was 60.00% , the two groups were statistically significant differences (P lt; 0.05), indicating that the treatment group in relieving symptoms of clinical efficacy was significantly than the control group . Two groups of patients before treatment Karnofsky score was no significant difference , but in the two groups after treatment Karnofsky score showed a significant difference (P lt; 0.05), indicating that the treatment group in improving the general condition of patients is superior to the control group . CEA in colorectal cancer have a certain diagnosis , two groups of patients before treatment CEA levels between the two groups was no significant difference in the after treatment showed a statistically significant difference , indicating lower CEA levels in the treatment group compared with the control group, there are aspects of certain advantages . Recent treated tumor objective response rate was 33.33% , slightly better than the control group 20.00% . No statistically significant difference (P gt; 0.05). Conclusion: Jianpihuashitang stasis detoxification side in the treatment of advanced colorectal cancer , with improved clinical symptoms and general condition of the body , reduce the side effects of chemotherapy and other effects, worthy of promotion.

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