Asymmetric Hydrogenation of Methyl Pyruvate and Acetophenone Catalyzed by Al2O3 Supported Pt Nanoclusters or Ru Catalyst
|Keywords||Supported catalyst Asymmetric hydrogenation Acetophenone Methyl pyruvate Enantioselective|
Catalytic hydrogenation of organic compounds containing carbonyl groups is an important field in a variety of chemical processes for the synthesis of fine chemical and pharmaceuticals.
The enantioselective hydrogenation of methyl pyruvate in the presence of γ-Al2O3 supported platinum nanoclusters and chiral modifier cinchonidine was investigated. The results showed that cinchonidine as a chiral modifier not only induced the enantioselectivity but also greatly accelerated the reaction rate. The effects of...