Clinical and Experimental Research on the Effect of Qingchang Mixture on Enterogenic Endotoxin and Serum Motiline of Acute Diffuse Peritonitis
|School||Shandong University of Traditional Chinese Medicine|
|Course||Surgery of Chinese Medicine|
|Keywords||Mixture bowel Acute diffuse peritonitis Intestinal endotoxemia Motilin|
Objective : To observe the bowel mixture on acute diffuse peritonitis intestinal endotoxemia and motilin effects . Methods: a clinical study, patients with acute diffuse peritonitis , and randomly divided into two groups : ( 1 ) the treatment group , ( 2 ) the control group , the treatment group with bowel mixture injected through the tube or enema administration. Two experimental studies through intraperitoneal injection of zymosan manufacturing animal models were randomly divided into three groups: ( 1 ) normal saline group , ( 2 ) Dachengqitang group , ( 3 ) bowel mixture group . Result: a clinical study found that the party has a satisfactory result , the total effective rate was 90.91% , better than the conventional treatment group , and no significant side effects. Intestinal endotoxemia , serum motilin levels compared with the control group, there were significant differences (P lt; 0.05). 2 Experimental studies have found three peripheral blood endotoxin, motilin levels , portal blood endotoxin levels were significantly different (P lt; 0.05). Conclusion: This prescription may be by promoting the secretion of motilin , increased gastrointestinal motility , and promote the excretion of endotoxin , thereby reducing endotoxemia, reduce endotoxin on body organs , tissue damage .