Dissertation > Industrial Technology > Chemical Industry > Pharmaceutical chemical industry > The Chinese herbal medicine preparations of the production

Philharmonic capsule technology and quality standard of

Author FanShiGen
Tutor GuoLi
School Chengdu University of Traditional Chinese Medicine
Course Medicinal Chemistry
Keywords AiLe capsule preparation process quality standard
Type Master's thesis
Year 2005
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The capsule of AiLe is comprised of Fructus Aurantii,Radix Curcumae,Herba Agrimoniae,Faeces Trogopterori,Semen Strychni,etc.Tt is applied mainly to treat cancer .The preparation process of this product were screened ,the quality standard was established and the preliminary stability was investigated.The test of quality and the basic stability of three batches have showed that the production technique is reasonable and practical,the quality is controllable,and the quality of the end product is stable.In the study of the preparation process,the optium diacolation and water extracting condition were selected by orthogonal experiment.Then we have explored the best conditions of the concentration and desiccation methods by single factor experiment.The homogeneity of mixed powder was examined in through the determination of Strychnine. We siered the kind of the adhesives and its dosage,then reviewed the bulk density,angle of repose and hygroscopicity of the granule.The quality standard established the thin layer chromatography identifiction of Fructus Aurantii, Radix Curcumae, Semen Strychni and each check all meets the standard of the pharmacopeia .The content of Naringin,Strychnine,Brucine in the preparation were measured by High Performance Liquid Chromatography.The studies showed that these

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