Dissertation
Dissertation > Medicine, health > Basic Medical > Medical science in general > Biomedical Engineering > Artificial organs and organ

Study on the Design and Biomechanical Behaviors of Individualized Artificial Knee Joint

Author MaNi
Tutor XiaoLiYing
School Tsinghua University
Course Mechanical Engineering
Keywords individualized artificial knee joint image segmentation finite element analysis kinematic/kinetic analysis
CLC R318.1
Type Master's thesis
Year 2010
Downloads 21
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In our country, the imported artificial knee joints are used in most clinical applications of knee arthroplasty. Artificial knee joint size study shows that the imports don’t match Chinese knee anatomy, which may result in surgical failure and reduction of the use life. Meanwhile, since there can be significant individual differences in knee anatomy, especially for patients with severe deformities, it is often difficult to meet patients’specific needs. Research on individualized artificial knee joint technology has important practical significance. At present, the design focuses on the reproduction in anatomy, lacking necessary design study and functional verification. In view of this, the paper explored a more advanced process for individualized artificial knee joint design:1. Based on modern computer technology, medical images of human knee joint were processed with image segmentation algorithms, and a three-dimensional solid model of the knee was established. The initial design was based on the anatomical structure of the knee, with combination of knee surgery standard and knee implant design theory. Meanwhile, considering patients with severe damage, the rectification of lower limb alignment and defects had to be taken into account. All degrees of freedom were examined to make sure that the motion scope of the artificial knee joint can meet the functional requirements of daily life.2. Considering the mechanical factors of terminal complications after total knee replacement, finite element analysis software was used for sensitivity analysis and optimization analysis to study the design parameters, find key parameters and the optimal parameters automatically.3. In order to obtain the biomechanics of TKR components, four lower limb models including ligaments and muscles were established and used to simulate the motions of healthy human and TKR patient in normal gait and squat dynamically. The TKR patient’s models involved the addition of the geometry for a total knee replacement system. The outputs included joint contact forces and knee joint related ligaments / muscles forces, and can be used to evaluate the artificial knee joint’s kinematic/kinetic performance through comparative analysis.

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